Detailed information of TA system TA058151

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapC-vagC/VapC-VagC
• Location: 226535..227172
• Replicon: chromosome
• Accession: NZ_CP013232
• Organism: Collimonas fungivorans strain Ter6

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: CFter6_RS01005
• Protein ID: WP_061538366.1
• Coordinates: 226771..227172 (+)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: A0A127P551
• Locus tag: CFter6_RS01000
• Protein ID: WP_061538365.1
• Coordinates: 226535..226771 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CFter6_RS00985	222929..224581	+	1653	WP_061538362.1	alpha,alpha-trehalase TreF	-
CFter6_RS00990	224578..225771	-	1194	WP_061538363.1	MFS transporter	-
CFter6_RS00995	225944..226423	+	480	WP_061538364.1	nuclear transport factor 2 family protein	-
CFter6_RS01000	226535..226771	+	237	WP_061538365.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CFter6_RS01005	226771..227172	+	402	WP_061538366.1	type II toxin-antitoxin system VapC family toxin	Toxin
CFter6_RS01010	227195..227467	-	273	WP_061538367.1	hypothetical protein	-
CFter6_RS01015	227816..229855	+	2040	WP_061538368.1	M3 family metallopeptidase	-
CFter6_RS01020	229965..230909	-	945	WP_082814504.1	S1/P1 nuclease	-
CFter6_RS01025	231147..231809	+	663	WP_061538370.1	epoxyqueuosine reductase QueH	-
CFter6_RS01030	231806..232024	+	219	WP_061538371.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-122)

Antitoxin

• SpoVT-AbrB domain (7-57)

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 14904.09 Da
• Isoelectric Point: 6.2250

>T58151 WP_061538366.1 NZ_CP013232:226771-227172 [Collimonas fungivorans]
MPRYMLDTNMCIYLMKNQPQQVAQRFAECFVGDVVMSAITFAELEYGVTISANQARERRNLHALIEDIPVAAFGSGAASA
YGPIREATRERKKDHLDKLIAAHAVSLDIILVTSNERDFASYPGVRIENWITV

Nucleotide

• Length: 402 bp

>T58151 NZ_CP013232:226771-227172 [Collimonas fungivorans]
ATGCCACGTTATATGCTCGACACCAATATGTGCATCTACCTGATGAAAAATCAGCCGCAGCAAGTGGCGCAGCGATTCGC
CGAATGTTTTGTCGGCGATGTCGTGATGTCGGCCATCACCTTTGCGGAGCTGGAGTATGGTGTCACGATATCCGCAAACC
AAGCGCGGGAGCGACGTAACCTGCACGCCTTGATAGAGGATATTCCTGTGGCGGCGTTTGGTAGCGGCGCTGCAAGCGCC
TACGGTCCGATTCGAGAGGCTACTCGGGAGCGCAAGAAAGATCATCTCGACAAATTGATTGCAGCGCATGCTGTATCGCT
CGATATCATCCTCGTTACCAGCAATGAGCGGGATTTCGCAAGTTATCCCGGCGTCAGAATAGAGAACTGGATTACAGTCT
AA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8891.05 Da
• Isoelectric Point: 5.8701

>AT58151 WP_061538365.1 NZ_CP013232:226535-226771 [Collimonas fungivorans]
MQTTKVFKNGNSQAVRIPADLAYERTDIELEIERVGDELRIRPVGRTLGGVLKKFAKFGPDFMSKGRDDHEQDEREAL

Nucleotide

• Length: 237 bp

>AT58151 NZ_CP013232:226535-226771 [Collimonas fungivorans]
ATGCAAACCACTAAAGTTTTTAAAAACGGCAACTCTCAGGCGGTCCGTATTCCAGCTGACCTGGCGTATGAGCGCACGGA
TATAGAGTTGGAGATAGAGCGTGTCGGCGACGAATTGCGGATTCGTCCAGTTGGAAGAACCCTGGGCGGGGTTTTAAAGA
AATTCGCGAAATTCGGACCGGATTTCATGAGTAAGGGCCGGGATGATCACGAGCAAGACGAACGCGAGGCTTTGTAA

Structures

Antitoxin

• AlphaFold DB: A0A127P551