Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 19570..20117 Replicon plasmid PDM04
Accession NZ_CP013224
Organism Salmonella enterica subsp. enterica serovar Anatum strain GT-38

Toxin (Protein)


Gene name parE Uniprot ID E9LLH3
Locus tag AS586_RS00105 Protein ID WP_000969996.1
Coordinates 19836..20117 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID K4JYR0
Locus tag AS586_RS00100 Protein ID WP_000079928.1
Coordinates 19570..19839 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS586_RS00080 14712..14999 - 288 WP_000074849.1 conjugal transfer protein TraA -
AS586_RS24090 14917..15180 - 264 WP_001324596.1 ash family protein -
AS586_RS00090 16153..17184 + 1032 WP_000907875.1 replication initiation protein -
AS586_RS00095 18167..19177 - 1011 WP_000487119.1 IS110 family transposase -
AS586_RS00100 19570..19839 + 270 WP_000079928.1 hypothetical protein Antitoxin
AS586_RS00105 19836..20117 + 282 WP_000969996.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AS586_RS00110 20157..21005 + 849 WP_001057996.1 3'-5' exonuclease -
AS586_RS26610 21242..21367 - 126 Protein_23 MerR family transcriptional regulator -
AS586_RS00115 21323..22972 + 1650 WP_000896475.1 DDE-type integrase/transposase/recombinase -
AS586_RS00120 22975..23835 + 861 WP_000344784.1 TniB family NTP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..112176 112176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(3-50)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T58134 WP_000969996.1 NZ_CP013224:19836-20117 [Salmonella enterica subsp. enterica serovar Anatum]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T58134 NZ_CP013224:19836-20117 [Salmonella enterica subsp. enterica serovar Anatum]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 11553.68 Da        Isoelectric Point: 12.7493

>AT58134 WP_000079928.1 NZ_CP013224:19570-19839 [Salmonella enterica subsp. enterica serovar Anatum]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKK

Download         Length: 270 bp

>AT58134 NZ_CP013224:19570-19839 [Salmonella enterica subsp. enterica serovar Anatum]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E9LLH3

Antitoxin

Source ID Structure
AlphaFold DB A0A5W2J4D0

References