Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 92060..92607 Replicon plasmid PDM02
Accession NZ_CP013221
Organism Salmonella enterica subsp. enterica serovar Anatum strain GT-01

Toxin (Protein)


Gene name parE Uniprot ID E9LLH3
Locus tag AS587_RS00470 Protein ID WP_000969996.1
Coordinates 92060..92341 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID K4JYR0
Locus tag AS587_RS00475 Protein ID WP_000079928.1
Coordinates 92338..92607 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS587_RS00455 88342..89202 - 861 WP_000344784.1 TniB family NTP-binding protein -
AS587_RS00460 89205..90854 - 1650 WP_000896475.1 DDE-type integrase/transposase/recombinase -
AS587_RS26570 90810..90935 + 126 Protein_97 MerR family transcriptional regulator -
AS587_RS00465 91172..92020 - 849 WP_001057996.1 3'-5' exonuclease -
AS587_RS00470 92060..92341 - 282 WP_000969996.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AS587_RS00475 92338..92607 - 270 WP_000079928.1 hypothetical protein Antitoxin
AS587_RS00480 93000..94010 + 1011 WP_000487119.1 IS110 family transposase -
AS587_RS00485 94993..96024 - 1032 WP_000907875.1 replication initiation protein -
AS587_RS24475 96997..97260 + 264 WP_001324596.1 ash family protein -
AS587_RS00495 97178..97465 + 288 WP_000074849.1 conjugal transfer protein TraA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..112176 112176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(5-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-65)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T58133 WP_000969996.1 NZ_CP013221:c92341-92060 [Salmonella enterica subsp. enterica serovar Anatum]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T58133 NZ_CP013221:c92341-92060 [Salmonella enterica subsp. enterica serovar Anatum]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Antitoxin


Download         Length: 90 a.a.        Molecular weight: 13263.91 Da        Isoelectric Point: 5.5500

>AT58133 WP_000079928.1 NZ_CP013221:c92607-92338 [Salmonella enterica subsp. enterica serovar Anatum]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Download         Length: 270 bp

>AT58133 NZ_CP013221:c92607-92338 [Salmonella enterica subsp. enterica serovar Anatum]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E9LLH3

Antitoxin

Source ID Structure
AlphaFold DB A0A5W2J4D0

References