Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 1938388..1939025 Replicon chromosome
Accession NZ_CP013189
Organism Pseudohongiella spirulinae strain KCTC 32221

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PS2015_RS08865 Protein ID WP_058021865.1
Coordinates 1938609..1939025 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PS2015_RS08860 Protein ID WP_058021864.1
Coordinates 1938388..1938618 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS2015_RS08840 1935399..1935857 - 459 WP_082628065.1 low molecular weight phosphotyrosine protein phosphatase -
PS2015_RS08845 1935854..1937053 - 1200 WP_058021862.1 polysaccharide biosynthesis/export family protein -
PS2015_RS08850 1937336..1937830 - 495 WP_058021863.1 transcription/translation regulatory transformer protein RfaH -
PS2015_RS08855 1937827..1938168 - 342 WP_058023237.1 MarR family EPS-associated transcriptional regulator -
PS2015_RS08860 1938388..1938618 + 231 WP_058021864.1 hypothetical protein Antitoxin
PS2015_RS08865 1938609..1939025 + 417 WP_058021865.1 type II toxin-antitoxin system VapC family toxin Toxin
PS2015_RS08870 1939055..1939657 + 603 WP_058021866.1 hypothetical protein -
PS2015_RS08875 1939733..1939999 + 267 WP_058021867.1 DUF4160 domain-containing protein -
PS2015_RS08880 1940009..1940245 + 237 WP_058021868.1 DUF2442 domain-containing protein -
PS2015_RS08885 1940285..1940734 + 450 WP_058021869.1 transposase -
PS2015_RS08890 1940903..1942960 - 2058 WP_058023239.1 NAD-dependent DNA ligase LigA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - ddhA 1917267..1940734 23467


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15213.33 Da        Isoelectric Point: 6.6800

>T58088 WP_058021865.1 NZ_CP013189:1938609-1939025 [Pseudohongiella spirulinae]
MYLIDTNVISEARKGDRSNAGVRQFFREAVESGAPCFVSSITIGEIQRGISLCNHRGDQKQGLILQAWLDSVLENYASNI
LPFCKDCAQLWGHLCSPDTTNIIDKQLAATALCYDLTVVTRNVRHVAGTGVRVLDPFN

Download         Length: 417 bp

>T58088 NZ_CP013189:1938609-1939025 [Pseudohongiella spirulinae]
ATGTATTTAATCGACACCAACGTCATCAGCGAGGCCCGCAAGGGCGATCGCAGCAACGCCGGAGTACGGCAGTTTTTCCG
TGAGGCGGTAGAGTCGGGGGCGCCCTGTTTTGTCAGCAGCATCACGATCGGCGAGATACAGCGCGGCATCAGCCTCTGCA
ATCATCGTGGCGACCAGAAGCAAGGCCTTATACTGCAGGCTTGGCTGGATAGCGTGTTGGAGAACTACGCGTCCAATATT
TTGCCGTTTTGCAAGGACTGCGCTCAGCTGTGGGGACATCTTTGCTCGCCTGACACAACCAATATTATCGACAAGCAACT
TGCCGCGACGGCGCTGTGTTATGACTTAACTGTGGTGACGCGGAATGTGCGGCATGTGGCGGGCACTGGGGTACGGGTGT
TGGATCCGTTTAATTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8165.32 Da        Isoelectric Point: 6.4580

>AT58088 WP_058021864.1 NZ_CP013189:1938388-1938618 [Pseudohongiella spirulinae]
MANLLVRNVDEDIVLALKKRAGAHGISAEAEHRRILEQALRGPRARSFAEVLAAMPDAGLDADFARPASAGRDECI

Download         Length: 231 bp

>AT58088 NZ_CP013189:1938388-1938618 [Pseudohongiella spirulinae]
ATGGCAAATCTGTTGGTCAGAAATGTGGACGAAGACATTGTACTGGCGCTGAAAAAGCGGGCCGGCGCACATGGCATTAG
TGCAGAGGCGGAACATCGGCGCATTCTGGAGCAGGCCCTGCGTGGCCCGCGCGCCCGGTCATTTGCGGAGGTGCTGGCAG
CGATGCCGGATGCCGGGCTGGATGCTGATTTTGCCCGACCTGCCTCAGCCGGGCGGGACGAATGTATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References