Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/PRK09907-MazE
Location 1852604..1853188 Replicon chromosome
Accession NZ_CP013189
Organism Pseudohongiella spirulinae strain KCTC 32221

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PS2015_RS08460 Protein ID WP_058021789.1
Coordinates 1852859..1853188 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PS2015_RS08455 Protein ID WP_058023224.1
Coordinates 1852604..1852858 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS2015_RS08435 1848458..1848826 - 369 WP_058021785.1 flagellar hook-basal body complex protein FliE -
PS2015_RS08440 1848832..1850232 - 1401 WP_058021786.1 sigma-54 dependent transcriptional regulator -
PS2015_RS08445 1850232..1851437 - 1206 WP_058021787.1 PAS domain-containing protein -
PS2015_RS08450 1852141..1852506 + 366 WP_058021788.1 hypothetical protein -
PS2015_RS08455 1852604..1852858 + 255 WP_058023224.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PS2015_RS08460 1852859..1853188 + 330 WP_058021789.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PS2015_RS08465 1853210..1853926 - 717 WP_058021790.1 GAP family protein -
PS2015_RS08470 1854230..1854799 - 570 WP_058021791.1 dCTP deaminase -
PS2015_RS08475 1854826..1856373 - 1548 WP_082628051.1 trypsin-like peptidase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-107)

Antitoxin

SpoVT-AbrB domain

(6-44)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12100.97 Da        Isoelectric Point: 8.9953

>T58087 WP_058021789.1 NZ_CP013189:1852859-1853188 [Pseudohongiella spirulinae]
MAYIPARGDIIWTDFDPSAGHEQARRRPAIVLSPEVFNWQIKLALVAPITSRIRGHGFEVHLQGTTTQGAVLCQQVKTID
YDYRGVKFIEAAPTGVLNEVLAKVRTLVT

Download         Length: 330 bp

>T58087 NZ_CP013189:1852859-1853188 [Pseudohongiella spirulinae]
ATGGCTTATATCCCTGCGCGTGGCGACATTATATGGACAGACTTCGACCCGTCCGCCGGGCACGAGCAGGCACGACGGCG
TCCTGCGATTGTGCTCTCTCCCGAGGTCTTCAACTGGCAGATCAAACTGGCACTGGTCGCCCCCATAACCAGTCGGATAC
GCGGACACGGTTTTGAGGTCCACCTGCAGGGAACCACGACGCAGGGTGCTGTGCTATGTCAGCAGGTCAAAACCATCGAC
TACGACTATCGCGGCGTTAAATTCATTGAGGCCGCTCCCACCGGCGTGTTAAACGAGGTGCTCGCCAAGGTACGCACCCT
TGTAACATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9134.29 Da        Isoelectric Point: 4.1830

>AT58087 WP_058023224.1 NZ_CP013189:1852604-1852858 [Pseudohongiella spirulinae]
MQTNIRKWGNSAGTIIPAPVLAEAGLRVGDAIQIEVVDGTIVIRQAAPVYRLEDLLEATPSDKLALDDEDKQWLHDAPVG
RESD

Download         Length: 255 bp

>AT58087 NZ_CP013189:1852604-1852858 [Pseudohongiella spirulinae]
ATGCAAACAAATATTCGCAAATGGGGCAACTCAGCGGGGACCATCATACCTGCACCGGTGCTGGCAGAGGCTGGACTGCG
TGTGGGTGATGCAATACAAATCGAAGTCGTGGATGGAACGATTGTGATCCGGCAGGCTGCTCCTGTTTACCGACTGGAGG
ACCTTCTGGAAGCGACCCCGTCAGACAAGTTGGCACTCGACGACGAGGATAAGCAGTGGCTTCATGATGCTCCTGTGGGC
AGGGAGTCCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References