Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 236311..236867 Replicon chromosome
Accession NZ_CP013189
Organism Pseudohongiella spirulinae strain KCTC 32221

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PS2015_RS01200 Protein ID WP_058023079.1
Coordinates 236556..236867 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PS2015_RS01195 Protein ID WP_058020451.1
Coordinates 236311..236568 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS2015_RS01130 231372..231947 + 576 WP_058020439.1 hypothetical protein -
PS2015_RS01135 232073..232531 + 459 WP_058020440.1 hypothetical protein -
PS2015_RS01145 232720..233001 + 282 WP_058020442.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
PS2015_RS01150 233001..233300 + 300 WP_058023078.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01160 233690..234028 + 339 WP_058020444.1 toxin-antitoxin system HicB family antitoxin -
PS2015_RS01165 234080..234304 - 225 WP_058020445.1 CopG family transcriptional regulator -
PS2015_RS01170 234309..234731 - 423 WP_058020446.1 putative toxin-antitoxin system toxin component, PIN family -
PS2015_RS01175 234922..235200 + 279 WP_058020447.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
PS2015_RS01180 235204..235464 + 261 WP_058020448.1 helix-turn-helix domain-containing protein -
PS2015_RS01185 235590..235868 + 279 WP_058020449.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01190 235878..236165 + 288 WP_058020450.1 HigA family addiction module antidote protein -
PS2015_RS01195 236311..236568 + 258 WP_058020451.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PS2015_RS01200 236556..236867 + 312 WP_058023079.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS2015_RS01205 237007..237321 + 315 WP_058020452.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01210 237308..237586 + 279 WP_058020453.1 putative addiction module antidote protein -
PS2015_RS01215 237735..237998 + 264 WP_058020454.1 BrnT family toxin -
PS2015_RS01220 237988..238257 + 270 WP_058020455.1 hypothetical protein -
PS2015_RS01225 238326..238628 + 303 WP_058020456.1 type II toxin-antitoxin system HigB family toxin -
PS2015_RS01230 238637..239017 + 381 WP_058020457.1 hypothetical protein -
PS2015_RS01235 239141..239383 + 243 WP_058023080.1 hypothetical protein -
PS2015_RS01240 239428..239706 + 279 WP_058020458.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01245 239706..239999 + 294 WP_058020459.1 HigA family addiction module antidote protein -
PS2015_RS01250 240073..240465 - 393 WP_058020460.1 PIN domain nuclease -
PS2015_RS01255 240462..240656 - 195 WP_058020461.1 type II toxin-antitoxin system VapB family antitoxin -
PS2015_RS01260 240839..241093 + 255 WP_058020462.1 type II toxin-antitoxin system HicA family toxin -
PS2015_RS01265 241090..241428 + 339 WP_058020463.1 type II toxin-antitoxin system HicB family antitoxin -
PS2015_RS01270 241505..241777 - 273 WP_058020464.1 BrnA antitoxin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 226994..240465 13471
- inside Prophage - - 237007..239999 2992


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12026.70 Da        Isoelectric Point: 4.4238

>T58082 WP_058023079.1 NZ_CP013189:236556-236867 [Pseudohongiella spirulinae]
VAEVVWTDPALDQLEEIAEYIALDKPSAASNLVKTIFSTVERLEQFPESGHAPPELPDSIYRELYVRPCRIFYRKEDNVA
LILHVMREERQLRRFLLEPELDS

Download         Length: 312 bp

>T58082 NZ_CP013189:236556-236867 [Pseudohongiella spirulinae]
GTGGCTGAAGTAGTATGGACAGACCCGGCGTTGGATCAGTTAGAGGAGATCGCGGAATACATTGCGCTGGATAAGCCAAG
CGCGGCTTCCAACCTTGTGAAGACGATCTTCTCTACAGTTGAACGGCTTGAGCAATTCCCGGAGTCTGGCCATGCGCCAC
CAGAGCTGCCAGATTCGATCTACCGAGAGCTGTATGTTAGACCTTGCCGGATCTTCTATCGCAAGGAAGATAACGTTGCT
CTTATCCTGCACGTCATGAGAGAAGAAAGGCAGCTACGCAGATTTCTATTAGAACCTGAGTTGGACAGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9764.35 Da        Isoelectric Point: 9.9289

>AT58082 WP_058020451.1 NZ_CP013189:236311-236568 [Pseudohongiella spirulinae]
MKVELVTNLKRQATKILADLHESKEAVLITEHGQPSAYLVDVQDYEFMQRRLALLEGLSKGERAILEGKTTSHSKAKERM
QKWLK

Download         Length: 258 bp

>AT58082 NZ_CP013189:236311-236568 [Pseudohongiella spirulinae]
ATGAAAGTTGAACTAGTCACCAACCTCAAGCGTCAAGCAACGAAGATTCTGGCTGATTTGCACGAAAGCAAAGAGGCCGT
CTTGATAACCGAACATGGCCAGCCGTCCGCCTACCTGGTTGATGTTCAGGACTATGAGTTTATGCAGCGCAGACTGGCGC
TGCTGGAAGGATTGTCCAAGGGAGAGCGGGCAATTCTGGAGGGCAAGACAACCTCCCATAGTAAAGCCAAGGAGCGGATG
CAGAAGTGGCTGAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References