Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 232720..233300 Replicon chromosome
Accession NZ_CP013189
Organism Pseudohongiella spirulinae strain KCTC 32221

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PS2015_RS01150 Protein ID WP_058023078.1
Coordinates 233001..233300 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PS2015_RS01145 Protein ID WP_058020442.1
Coordinates 232720..233001 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS2015_RS01115 227989..229011 + 1023 WP_058020437.1 hypothetical protein -
PS2015_RS15690 229001..230608 + 1608 WP_058020438.1 hypothetical protein -
PS2015_RS01125 230704..231237 + 534 WP_058023077.1 GrpB family protein -
PS2015_RS01130 231372..231947 + 576 WP_058020439.1 hypothetical protein -
PS2015_RS01135 232073..232531 + 459 WP_058020440.1 hypothetical protein -
PS2015_RS01145 232720..233001 + 282 WP_058020442.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PS2015_RS01150 233001..233300 + 300 WP_058023078.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS2015_RS01160 233690..234028 + 339 WP_058020444.1 toxin-antitoxin system HicB family antitoxin -
PS2015_RS01165 234080..234304 - 225 WP_058020445.1 CopG family transcriptional regulator -
PS2015_RS01170 234309..234731 - 423 WP_058020446.1 putative toxin-antitoxin system toxin component, PIN family -
PS2015_RS01175 234922..235200 + 279 WP_058020447.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
PS2015_RS01180 235204..235464 + 261 WP_058020448.1 helix-turn-helix domain-containing protein -
PS2015_RS01185 235590..235868 + 279 WP_058020449.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01190 235878..236165 + 288 WP_058020450.1 HigA family addiction module antidote protein -
PS2015_RS01195 236311..236568 + 258 WP_058020451.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
PS2015_RS01200 236556..236867 + 312 WP_058023079.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01205 237007..237321 + 315 WP_058020452.1 type II toxin-antitoxin system RelE/ParE family toxin -
PS2015_RS01210 237308..237586 + 279 WP_058020453.1 putative addiction module antidote protein -
PS2015_RS01215 237735..237998 + 264 WP_058020454.1 BrnT family toxin -
PS2015_RS01220 237988..238257 + 270 WP_058020455.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 226994..240465 13471
- inside Prophage - - 237007..239999 2992


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-74)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11223.95 Da        Isoelectric Point: 4.5702

>T58080 WP_058023078.1 NZ_CP013189:233001-233300 [Pseudohongiella spirulinae]
IMIEWSPLALERAGEIAAYIALDKPTAAESWLDGLFESVERLEPHPMSGRVVPEINIERIREVIYGAYRVIYRVDTQAKK
ISVLTVLRGSELIRADELD

Download         Length: 300 bp

>T58080 NZ_CP013189:233001-233300 [Pseudohongiella spirulinae]
ATTATGATTGAATGGTCGCCGCTCGCATTGGAAAGGGCGGGTGAAATTGCTGCCTATATCGCGCTGGATAAACCCACCGC
TGCAGAGTCATGGCTAGACGGACTGTTCGAATCGGTAGAGCGCTTGGAGCCGCACCCAATGAGCGGTCGCGTTGTCCCTG
AAATCAACATTGAGCGAATTCGAGAAGTCATTTATGGTGCGTATCGTGTTATTTATCGCGTTGATACTCAAGCAAAAAAA
ATTTCAGTGCTTACGGTTCTGCGTGGCAGCGAATTAATTCGGGCTGATGAGCTCGATTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10623.18 Da        Isoelectric Point: 7.3192

>AT58080 WP_058020442.1 NZ_CP013189:232720-233001 [Pseudohongiella spirulinae]
MTKLRVDEDIRPLSDFRAGIASFVKQINETHRPMVLTQRGRGVAVLVGVHEYQKMQQRLELLEDIYRAEAQIEAGEGVPH
AEAKNQLLSQLRQ

Download         Length: 282 bp

>AT58080 NZ_CP013189:232720-233001 [Pseudohongiella spirulinae]
ATGACTAAGTTGAGAGTTGATGAGGATATTCGCCCGCTGTCCGACTTCAGGGCAGGCATAGCCTCCTTTGTAAAGCAGAT
TAACGAGACTCATCGCCCCATGGTCCTTACTCAGCGTGGCCGCGGGGTTGCTGTGCTGGTTGGCGTGCATGAATATCAAA
AGATGCAGCAGCGTCTGGAGTTGCTTGAGGACATCTATCGGGCAGAGGCGCAAATCGAAGCGGGAGAAGGCGTTCCCCAC
GCAGAGGCAAAGAATCAGTTACTGAGTCAGCTACGCCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References