Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3112431..3113706 Replicon chromosome
Accession NZ_CP013184
Organism Pseudomonas protegens strain H78

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H78_RS14555 Protein ID WP_077933991.1
Coordinates 3113107..3113706 (+) Length 200 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H78_RS14550 Protein ID WP_123725179.1
Coordinates 3112431..3112988 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H78_RS14520 3107636..3108286 + 651 WP_077933987.1 DUF2239 family protein -
H78_RS14525 3108374..3108994 + 621 WP_077933988.1 LysE family translocator -
H78_RS14530 3109040..3109627 - 588 WP_065363866.1 inclusion body family protein -
H78_RS14535 3110086..3111273 + 1188 WP_077933989.1 PrpF protein -
H78_RS14540 3111452..3111919 - 468 WP_077933990.1 hypothetical protein -
H78_RS14545 3111900..3112241 - 342 WP_041752202.1 low molecular weight protein tyrosine phosphatase family protein -
H78_RS14550 3112431..3112988 + 558 WP_123725179.1 helix-turn-helix domain-containing protein Antitoxin
H78_RS14555 3113107..3113706 + 600 WP_077933991.1 HD domain-containing protein Toxin
H78_RS14560 3113921..3116101 + 2181 WP_077933992.1 catalase/peroxidase HPI -
H78_RS14565 3116229..3116657 - 429 WP_011060992.1 hypothetical protein -
H78_RS14570 3116892..3117806 + 915 WP_077933993.1 SGNH/GDSL hydrolase family protein -
H78_RS14575 3118155..3118418 + 264 WP_077933994.1 hypothetical protein -
H78_RS14580 3118415..3118609 + 195 WP_077933995.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(8-187)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 200 a.a.        Molecular weight: 22467.27 Da        Isoelectric Point: 6.0243

>T58046 WP_077933991.1 NZ_CP013184:3113107-3113706 [Pseudomonas protegens]
MNSELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERADLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDVDTQRRLDAQAQAAVHHRLR

Download         Length: 600 bp

>T58046 NZ_CP013184:3113107-3113706 [Pseudomonas protegens]
ATGAACAGTGAACTTCTCAGTGGCCGCCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACGGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAGGCCATTCACGGCGACATCCCG
GCGGTGGCCCAGGCTGCCCACCCGGACAAGAGCCAGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGACGCCAGCCCGCTGTTCCAGGCCCTGCGCCAGCAGATCGACGTCGATACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCATCATCGGCTGCGCTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20397.32 Da        Isoelectric Point: 7.0307

>AT58046 WP_123725179.1 NZ_CP013184:3112431-3112988 [Pseudomonas protegens]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPAERVRLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSATRAGQFGVPLSELLGQSLWGFCTEEITRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT58046 NZ_CP013184:3112431-3112988 [Pseudomonas protegens]
ATGTCCGTAGCTCTGTTCACCTCCCCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAACTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGTTGGGAAAACGGCCAGCAGGCCATGGAACCGGCCG
AGCGTGTGCGCCTGGAACAACTGCTGGCGGCCAACCTCAGCGCCGCCGCTGACCAGGCCCTGGCGCGGCTGGTGAACGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCAGCGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGTGAGCTGCTGGGCCAGTCCCTGTGGGGCTTTTGCACCGAGGAAATCACCCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGTGAAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTCTCTGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References