Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1016288..1016826 Replicon chromosome
Accession NZ_CP013184
Organism Pseudomonas protegens strain H78

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H78_RS04505 Protein ID WP_072443006.1
Coordinates 1016548..1016826 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U9L9U0
Locus tag H78_RS04500 Protein ID WP_047283908.1
Coordinates 1016288..1016551 (+) Length 88 a.a.

Genomic Context

H78_RS04490H78_RS04495H78_RS04500H78_RS04505H78_RS04485H78_RS04510H78_RS04515H78_RS04520H78_RS04525
Location: 1014763..1015443 (681 bp)
Type: Others
Protein ID: WP_077933344.1
Location: 1015447..1016232 (786 bp)
Type: Others
Protein ID: WP_077933345.1
Location: 1016288..1016551 (264 bp)
Type: Antitoxin
Protein ID: WP_047283908.1
Location: 1016548..1016826 (279 bp)
Type: Toxin
Protein ID: WP_072443006.1
Location: 1012250..1014556 (2307 bp)
Type: Others
Protein ID: WP_065364619.1
Location: 1016897..1018060 (1164 bp)
Type: Others
Protein ID: WP_015634137.1
Location: 1018739..1019896 (1158 bp)
Type: Others
Protein ID: WP_011059224.1
Location: 1019893..1020546 (654 bp)
Type: Others
Protein ID: WP_011059225.1
Location: 1020559..1021452 (894 bp)
Type: Others
Protein ID: WP_015634139.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H78_RS044851012250..1014556-2307WP_065364619.1TonB-dependent siderophore receptor-
H78_RS044901014763..1015443+681WP_077933344.1Fe2+-dependent dioxygenase-
H78_RS044951015447..1016232+786WP_077933345.1sel1 repeat family protein-
H78_RS045001016288..1016551+264WP_047283908.1ribbon-helix-helix domain-containing proteinAntitoxin
H78_RS045051016548..1016826+279WP_072443006.1type II toxin-antitoxin system RelE/ParE family toxinToxin
H78_RS045101016897..1018060-1164WP_015634137.1type III PLP-dependent enzyme-
H78_RS045151018739..1019896-1158WP_011059224.1ABC transporter ATP-binding protein-
H78_RS045201019893..1020546-654WP_011059225.1ABC transporter permease-
H78_RS045251020559..1021452-894WP_015634139.1glycine betaine ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10793.48 Da        Isoelectric Point: 10.6604

>T58044 WP_072443006.1 NZ_CP013184:1016548-1016826 [Pseudomonas protegens]
MRQLKWTSKALSDLARLFEFLAQANRSTAARTVQSLVQAPDALLSNPRLGEQLEEFKPRDVRRLLVGHYEMRYEIQGMAL
SILRIWHVREDR

Download         Length: 279 bp

>T58044 NZ_CP013184:1016548-1016826 [Pseudomonas protegens]
ATGAGACAGCTGAAATGGACGAGCAAGGCCCTATCCGATCTGGCTCGGCTTTTTGAGTTTCTCGCCCAGGCCAATCGTTC
TACTGCTGCTCGGACCGTGCAATCGCTGGTGCAGGCTCCAGATGCTCTTCTATCTAACCCACGATTGGGAGAGCAGTTGG
AGGAATTCAAGCCGAGGGATGTTCGACGATTGCTGGTGGGGCATTACGAGATGCGTTATGAGATTCAAGGCATGGCCTTG
TCCATCCTGCGTATTTGGCATGTCCGGGAAGATCGTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9676.08 Da        Isoelectric Point: 5.6706

>AT58044 WP_047283908.1 NZ_CP013184:1016288-1016551 [Pseudomonas protegens]
MPATKVLTAHIPLDLADKVDQLASRLERSRAWVVKQALVAWVDQEEERRRLTLEALADVDAGRVVDHQSVLAWAQSLSGD
NPLPLPK

Download         Length: 264 bp

>AT58044 NZ_CP013184:1016288-1016551 [Pseudomonas protegens]
ATGCCCGCGACAAAAGTACTGACCGCTCACATTCCCTTGGACCTGGCTGACAAGGTCGATCAACTTGCTTCTCGCCTGGA
ACGCTCCCGGGCCTGGGTCGTGAAGCAGGCGTTGGTGGCCTGGGTTGACCAGGAAGAAGAGCGCCGTCGACTGACGCTTG
AGGCCTTGGCAGATGTCGATGCTGGAAGGGTTGTGGATCATCAGTCAGTGTTGGCTTGGGCGCAGAGTCTGTCTGGCGAC
AACCCTCTGCCCTTACCAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7U9L9U0

References