Detailed information of TA system TA058044

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1016288..1016826
• Replicon: chromosome
• Accession: NZ_CP013184
• Organism: Pseudomonas protegens strain H78

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: H78_RS04505
• Protein ID: WP_072443006.1
• Coordinates: 1016548..1016826 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7U9L9U0
• Locus tag: H78_RS04500
• Protein ID: WP_047283908.1
• Coordinates: 1016288..1016551 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H78_RS04485	1012250..1014556	-	2307	WP_065364619.1	TonB-dependent siderophore receptor	-
H78_RS04490	1014763..1015443	+	681	WP_077933344.1	Fe2+-dependent dioxygenase	-
H78_RS04495	1015447..1016232	+	786	WP_077933345.1	sel1 repeat family protein	-
H78_RS04500	1016288..1016551	+	264	WP_047283908.1	ribbon-helix-helix domain-containing protein	Antitoxin
H78_RS04505	1016548..1016826	+	279	WP_072443006.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H78_RS04510	1016897..1018060	-	1164	WP_015634137.1	type III PLP-dependent enzyme	-
H78_RS04515	1018739..1019896	-	1158	WP_011059224.1	ABC transporter ATP-binding protein	-
H78_RS04520	1019893..1020546	-	654	WP_011059225.1	ABC transporter permease	-
H78_RS04525	1020559..1021452	-	894	WP_015634139.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Ribbon-helix-helix protein, CopG (7-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10793.48 Da
• Isoelectric Point: 10.6604

>T58044 WP_072443006.1 NZ_CP013184:1016548-1016826 [Pseudomonas protegens]
MRQLKWTSKALSDLARLFEFLAQANRSTAARTVQSLVQAPDALLSNPRLGEQLEEFKPRDVRRLLVGHYEMRYEIQGMAL
SILRIWHVREDR

Nucleotide

• Length: 279 bp

>T58044 NZ_CP013184:1016548-1016826 [Pseudomonas protegens]
ATGAGACAGCTGAAATGGACGAGCAAGGCCCTATCCGATCTGGCTCGGCTTTTTGAGTTTCTCGCCCAGGCCAATCGTTC
TACTGCTGCTCGGACCGTGCAATCGCTGGTGCAGGCTCCAGATGCTCTTCTATCTAACCCACGATTGGGAGAGCAGTTGG
AGGAATTCAAGCCGAGGGATGTTCGACGATTGCTGGTGGGGCATTACGAGATGCGTTATGAGATTCAAGGCATGGCCTTG
TCCATCCTGCGTATTTGGCATGTCCGGGAAGATCGTTGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9676.08 Da
• Isoelectric Point: 5.6706

>AT58044 WP_047283908.1 NZ_CP013184:1016288-1016551 [Pseudomonas protegens]
MPATKVLTAHIPLDLADKVDQLASRLERSRAWVVKQALVAWVDQEEERRRLTLEALADVDAGRVVDHQSVLAWAQSLSGD
NPLPLPK

Nucleotide

• Length: 264 bp

>AT58044 NZ_CP013184:1016288-1016551 [Pseudomonas protegens]
ATGCCCGCGACAAAAGTACTGACCGCTCACATTCCCTTGGACCTGGCTGACAAGGTCGATCAACTTGCTTCTCGCCTGGA
ACGCTCCCGGGCCTGGGTCGTGAAGCAGGCGTTGGTGGCCTGGGTTGACCAGGAAGAAGAGCGCCGTCGACTGACGCTTG
AGGCCTTGGCAGATGTCGATGCTGGAAGGGTTGTGGATCATCAGTCAGTGTTGGCTTGGGCGCAGAGTCTGTCTGGCGAC
AACCCTCTGCCCTTACCAAAATGA

Structures

Antitoxin

• AlphaFold DB: A0A7U9L9U0