Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 762171..762767 Replicon chromosome
Accession NZ_CP013184
Organism Pseudomonas protegens strain H78

Toxin (Protein)


Gene name relE Uniprot ID A0A2C9EFT8
Locus tag H78_RS03345 Protein ID WP_015633982.1
Coordinates 762465..762767 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2C9EFR9
Locus tag H78_RS03340 Protein ID WP_015633981.1
Coordinates 762171..762461 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H78_RS03320 758441..760573 - 2133 WP_015633979.1 TonB-dependent copper receptor -
H78_RS03325 760662..761072 - 411 WP_011059017.1 DUF2946 domain-containing protein -
H78_RS03330 761128..761607 - 480 WP_026020078.1 copper chaperone PCu(A)C -
H78_RS03335 761672..762070 - 399 WP_011059019.1 DUF2946 domain-containing protein -
H78_RS03340 762171..762461 - 291 WP_015633981.1 putative addiction module antidote protein Antitoxin
H78_RS03345 762465..762767 - 303 WP_015633982.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H78_RS03350 762951..763679 - 729 WP_077933275.1 cobalt-precorrin-6A reductase -
H78_RS03355 763676..764773 - 1098 WP_077933276.1 cobalt-precorrin-5B (C(1))-methyltransferase -
H78_RS03360 764867..766081 - 1215 WP_011059024.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
H78_RS03365 766220..767533 + 1314 WP_077933277.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11504.34 Da        Isoelectric Point: 10.6512

>T58043 WP_015633982.1 NZ_CP013184:c762767-762465 [Pseudomonas protegens]
MFVFEQTPEFSRWLLNLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVHEMRIHRGPGYRVYFSRRGKVIYLLLIGGDKA
TQKRDIQRARQLACDLKSEG

Download         Length: 303 bp

>T58043 NZ_CP013184:c762767-762465 [Pseudomonas protegens]
ATGTTCGTTTTCGAGCAGACTCCTGAGTTCAGCCGCTGGCTGCTGAACCTGAAGGACCCGCAAGGGAAAACCCGTGTACT
GGCCAGGATCCGCGCCGCACAGCTGGGCCGTTTTGGCGACTGCGAACCTGTGGGCGAAGGCGTCCACGAGATGCGCATCC
ACCGCGGTCCGGGTTACCGGGTGTACTTCTCGCGCCGCGGCAAAGTGATCTACCTGCTGTTGATCGGCGGCGACAAGGCC
ACCCAGAAACGCGATATCCAACGGGCCAGGCAACTGGCCTGCGACCTCAAGAGCGAGGGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10422.96 Da        Isoelectric Point: 6.2901

>AT58043 WP_015633981.1 NZ_CP013184:c762461-762171 [Pseudomonas protegens]
MRTPVTRFDAAEYLKTPEDMVAYLNACFEEDTGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKINVSNA

Download         Length: 291 bp

>AT58043 NZ_CP013184:c762461-762171 [Pseudomonas protegens]
ATGCGCACCCCAGTGACCCGCTTCGACGCGGCGGAGTACCTCAAGACCCCTGAAGACATGGTCGCCTACCTCAACGCCTG
CTTCGAGGAAGACACCGGCGACGGCGTGCTGATCCGCGCCGCACTCAACGACATCGCCCGTGCCCGCGGCATGACCCAGG
TCGCCCGTGACACCGGCCTGGGCCGCGAAAGCCTGTACAAGGCCCTCGGCAGCCAGGGCAACCCGGAGTTCGCGACTATC
ATCAAGGTGATGAAGGCCCTGGGGTTGAAGATCAACGTCAGCAACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9EFT8

Antitoxin

Source ID Structure
AlphaFold DB A0A2C9EFR9

References