Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 762171..762767 Replicon chromosome
Accession NZ_CP013184
Organism Pseudomonas protegens strain H78

Toxin (Protein)


Gene name relE Uniprot ID A0A2C9EFT8
Locus tag H78_RS03345 Protein ID WP_015633982.1
Coordinates 762465..762767 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2C9EFR9
Locus tag H78_RS03340 Protein ID WP_015633981.1
Coordinates 762171..762461 (-) Length 97 a.a.

Genomic Context

H78_RS03365H78_RS03320H78_RS03325H78_RS03330H78_RS03335H78_RS03340H78_RS03345H78_RS03350H78_RS03355H78_RS03360
Location: 766220..767533 (1314 bp)
Type: Others
Protein ID: WP_077933277.1
Location: 758441..760573 (2133 bp)
Type: Others
Protein ID: WP_015633979.1
Location: 760662..761072 (411 bp)
Type: Others
Protein ID: WP_011059017.1
Location: 761128..761607 (480 bp)
Type: Others
Protein ID: WP_026020078.1
Location: 761672..762070 (399 bp)
Type: Others
Protein ID: WP_011059019.1
Location: 762171..762461 (291 bp)
Type: Antitoxin
Protein ID: WP_015633981.1
Location: 762465..762767 (303 bp)
Type: Toxin
Protein ID: WP_015633982.1
Location: 762951..763679 (729 bp)
Type: Others
Protein ID: WP_077933275.1
Location: 763676..764773 (1098 bp)
Type: Others
Protein ID: WP_077933276.1
Location: 764867..766081 (1215 bp)
Type: Others
Protein ID: WP_011059024.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H78_RS03320758441..760573-2133WP_015633979.1TonB-dependent copper receptor-
H78_RS03325760662..761072-411WP_011059017.1DUF2946 domain-containing protein-
H78_RS03330761128..761607-480WP_026020078.1copper chaperone PCu(A)C-
H78_RS03335761672..762070-399WP_011059019.1DUF2946 domain-containing protein-
H78_RS03340762171..762461-291WP_015633981.1putative addiction module antidote proteinAntitoxin
H78_RS03345762465..762767-303WP_015633982.1type II toxin-antitoxin system RelE/ParE family toxinToxin
H78_RS03350762951..763679-729WP_077933275.1cobalt-precorrin-6A reductase-
H78_RS03355763676..764773-1098WP_077933276.1cobalt-precorrin-5B (C(1))-methyltransferase-
H78_RS03360764867..766081-1215WP_011059024.1bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase-
H78_RS03365766220..767533+1314WP_077933277.1precorrin-3B synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11504.34 Da        Isoelectric Point: 10.6512

>T58043 WP_015633982.1 NZ_CP013184:c762767-762465 [Pseudomonas protegens]
MFVFEQTPEFSRWLLNLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVHEMRIHRGPGYRVYFSRRGKVIYLLLIGGDKA
TQKRDIQRARQLACDLKSEG

Download         Length: 303 bp

>T58043 NZ_CP013184:c762767-762465 [Pseudomonas protegens]
ATGTTCGTTTTCGAGCAGACTCCTGAGTTCAGCCGCTGGCTGCTGAACCTGAAGGACCCGCAAGGGAAAACCCGTGTACT
GGCCAGGATCCGCGCCGCACAGCTGGGCCGTTTTGGCGACTGCGAACCTGTGGGCGAAGGCGTCCACGAGATGCGCATCC
ACCGCGGTCCGGGTTACCGGGTGTACTTCTCGCGCCGCGGCAAAGTGATCTACCTGCTGTTGATCGGCGGCGACAAGGCC
ACCCAGAAACGCGATATCCAACGGGCCAGGCAACTGGCCTGCGACCTCAAGAGCGAGGGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10422.96 Da        Isoelectric Point: 6.2901

>AT58043 WP_015633981.1 NZ_CP013184:c762461-762171 [Pseudomonas protegens]
MRTPVTRFDAAEYLKTPEDMVAYLNACFEEDTGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKINVSNA

Download         Length: 291 bp

>AT58043 NZ_CP013184:c762461-762171 [Pseudomonas protegens]
ATGCGCACCCCAGTGACCCGCTTCGACGCGGCGGAGTACCTCAAGACCCCTGAAGACATGGTCGCCTACCTCAACGCCTG
CTTCGAGGAAGACACCGGCGACGGCGTGCTGATCCGCGCCGCACTCAACGACATCGCCCGTGCCCGCGGCATGACCCAGG
TCGCCCGTGACACCGGCCTGGGCCGCGAAAGCCTGTACAAGGCCCTCGGCAGCCAGGGCAACCCGGAGTTCGCGACTATC
ATCAAGGTGATGAAGGCCCTGGGGTTGAAGATCAACGTCAGCAACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A2C9EFT8

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2C9EFR9

References