Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2483340..2484135 Replicon chromosome
Accession NZ_CP013145
Organism Colwellia sp. MT41

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag CMT41_RS10585 Protein ID WP_058027226.1
Coordinates 2483340..2483747 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag CMT41_RS10590 Protein ID WP_058027227.1
Coordinates 2483749..2484135 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CMT41_RS10570 2479058..2480026 + 969 WP_058027223.1 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB -
CMT41_RS10575 2480414..2481772 + 1359 WP_058027224.1 deoxyguanosinetriphosphate triphosphohydrolase family protein -
CMT41_RS10580 2481812..2482936 + 1125 WP_058027225.1 hypothetical protein -
CMT41_RS10585 2483340..2483747 - 408 WP_058027226.1 DUF86 domain-containing protein Toxin
CMT41_RS10590 2483749..2484135 - 387 WP_058027227.1 nucleotidyltransferase domain-containing protein Antitoxin
CMT41_RS10595 2484327..2485226 - 900 WP_083494269.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
CMT41_RS10605 2485883..2486599 - 717 WP_058027230.1 WecB/TagA/CpsF family glycosyltransferase -
CMT41_RS10610 2486587..2487651 - 1065 WP_058027231.1 glycosyltransferase family 4 protein -
CMT41_RS10615 2487781..2488824 - 1044 WP_058027232.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-131)

Antitoxin

Polymerase beta, nucleotidyltransferase

(8-97)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15224.43 Da        Isoelectric Point: 6.0822

>T58019 WP_058027226.1 NZ_CP013145:c2483747-2483340 [Colwellia sp. MT41]
MDDVLVNKLSTITRCLKRIREVYAEAGDNFSHDYTRQDSVILNLQRACEASIDIANYLNKNKQLAIPQSSRDSFQILTSA
GLISSSVATNLKKMIGLGNIAVHDYKELNMDIVEAVINHHLVDFELFISEIKKEL

Download         Length: 408 bp

>T58019 NZ_CP013145:c2483747-2483340 [Colwellia sp. MT41]
ATGGATGATGTTTTAGTAAATAAATTATCGACGATTACTCGTTGCTTAAAGCGTATTCGTGAAGTTTATGCGGAAGCAGG
GGATAACTTCTCTCATGATTATACCCGGCAGGACTCTGTTATTTTAAATTTGCAACGTGCTTGTGAAGCTTCTATTGATA
TTGCTAATTATTTGAATAAAAATAAGCAATTGGCAATACCGCAAAGTAGTCGTGATAGCTTTCAAATTCTGACTTCTGCA
GGACTTATTTCATCATCTGTGGCGACTAATTTAAAGAAGATGATTGGACTAGGTAATATAGCGGTTCATGACTATAAAGA
GTTAAATATGGATATTGTAGAAGCGGTAATTAACCATCACCTGGTCGACTTTGAATTATTTATTAGTGAAATTAAGAAAG
AGCTTTAA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14618.70 Da        Isoelectric Point: 4.4325

>AT58019 WP_058027227.1 NZ_CP013145:c2484135-2483749 [Colwellia sp. MT41]
MVIDLNTQLITALKQYFPDIKLLYLFGSHVSNQAHKNSDIDLAVLLANKISTVTRWEIQQELAVEFNVDVDLIDLLSAST
VMQNEIVNKGNCLYDAKDYKGEFEMQVMSMYQHLNEERSSLLTAFKGE

Download         Length: 387 bp

>AT58019 NZ_CP013145:c2484135-2483749 [Colwellia sp. MT41]
ATGGTCATTGATCTTAATACTCAGCTTATTACTGCCCTTAAACAGTATTTTCCTGATATAAAACTGTTATATTTATTTGG
TTCTCATGTGAGTAATCAAGCTCACAAAAACAGTGATATTGATTTAGCTGTGTTGTTAGCAAATAAGATCTCTACGGTAA
CTCGTTGGGAAATACAGCAAGAATTAGCGGTAGAATTTAATGTCGATGTCGATTTAATTGATTTATTATCCGCTTCGACA
GTGATGCAAAATGAAATTGTTAATAAAGGCAATTGTTTGTATGATGCTAAGGATTATAAGGGCGAATTTGAAATGCAAGT
AATGTCTATGTATCAGCATTTAAATGAAGAACGGTCATCGTTATTAACGGCATTTAAAGGAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References