Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2011916..2012441 Replicon chromosome
Accession NZ_CP013145
Organism Colwellia sp. MT41

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CMT41_RS08630 Protein ID WP_058027036.1
Coordinates 2011916..2012203 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CMT41_RS08635 Protein ID WP_057180920.1
Coordinates 2012193..2012441 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CMT41_RS08595 2007018..2007293 + 276 WP_058027033.1 helix-turn-helix domain-containing protein -
CMT41_RS08600 2007580..2008644 - 1065 WP_058027034.1 IS91 family transposase -
CMT41_RS08605 2008637..2009548 - 912 WP_057180813.1 site-specific integrase -
CMT41_RS19370 2009762..2010052 + 291 WP_057183207.1 SEC-C domain-containing protein -
CMT41_RS08615 2010448..2010903 - 456 WP_058027035.1 hypothetical protein -
CMT41_RS08620 2011253..2011492 - 240 WP_057180917.1 DUF2442 domain-containing protein -
CMT41_RS08625 2011503..2011772 - 270 WP_057180918.1 DUF4160 domain-containing protein -
CMT41_RS08630 2011916..2012203 - 288 WP_058027036.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CMT41_RS08635 2012193..2012441 - 249 WP_057180920.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CMT41_RS19070 2012739..2012876 + 138 WP_143760135.1 DUF4177 domain-containing protein -
CMT41_RS08640 2013136..2014359 + 1224 WP_058027037.1 sodium/glutamate symporter -
CMT41_RS08645 2014525..2015499 + 975 WP_058027038.1 hypothetical protein -
CMT41_RS08650 2015873..2016106 + 234 WP_057180923.1 CopG family transcriptional regulator -
CMT41_RS08655 2016093..2016356 + 264 WP_057180924.1 type II toxin-antitoxin system RelE/ParE family toxin -
CMT41_RS08660 2016689..2017303 + 615 WP_057180925.1 LysE family translocator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10972.03 Da        Isoelectric Point: 10.5954

>T58018 WP_058027036.1 NZ_CP013145:c2012203-2011916 [Colwellia sp. MT41]
MTYELEFKKSALKEWKKLGAIVKLQFKKKLANILENPHIESAKLSGDNKLYKIKLRQVGYRLVYEVSDTVITVTVISVGK
RDRGKVYKAAMERLN

Download         Length: 288 bp

>T58018 NZ_CP013145:c2012203-2011916 [Colwellia sp. MT41]
ATGACCTATGAGTTGGAGTTTAAAAAGTCTGCACTTAAGGAATGGAAAAAATTAGGTGCAATAGTTAAATTACAGTTCAA
GAAAAAACTTGCAAACATTTTAGAAAATCCTCATATAGAAAGTGCCAAGCTCTCAGGTGACAATAAATTATACAAAATAA
AACTTAGACAGGTCGGTTATAGACTAGTTTACGAGGTAAGCGATACAGTTATTACTGTCACCGTAATTTCTGTTGGGAAG
CGTGATAGAGGAAAAGTATACAAAGCCGCGATGGAGCGCCTCAATTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.46 Da        Isoelectric Point: 4.2837

>AT58018 WP_057180920.1 NZ_CP013145:c2012441-2012193 [Colwellia sp. MT41]
MTTRILTEAAASISELKANPMKVALSAHGEAIAVLNRNEPAFYCIPAETYEFMMDYIEDLELLAIVEQRKSEASVKVSLN
DL

Download         Length: 249 bp

>AT58018 NZ_CP013145:c2012441-2012193 [Colwellia sp. MT41]
ATGACAACTAGAATATTAACTGAAGCTGCGGCAAGTATTAGTGAACTTAAAGCAAATCCAATGAAGGTTGCTCTTAGTGC
TCACGGCGAAGCAATTGCAGTGCTAAATAGAAACGAACCTGCATTTTATTGTATACCGGCAGAGACTTATGAGTTTATGA
TGGACTATATTGAAGATTTAGAGCTACTTGCCATTGTTGAGCAGCGTAAAAGTGAAGCTAGTGTAAAGGTTAGTTTAAAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References