Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 5173465..5174321 Replicon chromosome
Accession NZ_CP013136
Organism Herbaspirillum seropedicae strain AU14040

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag hsc_RS22605 Protein ID WP_069375273.1
Coordinates 5173465..5173986 (-) Length 174 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag hsc_RS22610 Protein ID WP_083247246.1
Coordinates 5173983..5174321 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
hsc_RS22585 5168612..5170174 - 1563 WP_069375270.1 MCP four helix bundle domain-containing protein -
hsc_RS22590 5170330..5171166 - 837 WP_069375271.1 amidohydrolase family protein -
hsc_RS22595 5171163..5172404 - 1242 WP_013236516.1 MFS transporter -
hsc_RS22600 5172705..5173439 + 735 WP_069375272.1 GntR family transcriptional regulator -
hsc_RS22605 5173465..5173986 - 522 WP_069375273.1 RES family NAD+ phosphorylase Toxin
hsc_RS22610 5173983..5174321 - 339 WP_083247246.1 hypothetical protein Antitoxin
hsc_RS22615 5174950..5175627 + 678 WP_069375275.1 glutathione transferase -
hsc_RS22620 5175731..5176987 - 1257 WP_083247206.1 MFS transporter -
hsc_RS22625 5177449..5178171 + 723 WP_069375277.1 FadR family transcriptional regulator -
hsc_RS22630 5178255..5179058 - 804 WP_069375278.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(10-165)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19261.94 Da        Isoelectric Point: 5.2325

>T57991 WP_069375273.1 NZ_CP013136:c5173986-5173465 [Herbaspirillum seropedicae]
MILTPLQTVAYRVHSPRWAYAPLSGQGAARFGGRLNRPGVEALYLSLEPATALAEYQQFDDLLPPGLVVTYMVKIDPVVD
FRGGLDEAWNSAWAEFYCDWRSVVFQEKREPPSWALGEQARAAGAKGILFRSSVLKEGCNLVVFNRTLTDQDLISIHDPG
GELPLNQLSWPRS

Download         Length: 522 bp

>T57991 NZ_CP013136:c5173986-5173465 [Herbaspirillum seropedicae]
ATGATCCTGACTCCATTGCAGACGGTGGCTTATCGCGTCCATTCCCCGCGATGGGCTTATGCCCCACTGTCGGGACAAGG
GGCTGCGCGTTTTGGCGGCCGGCTCAACAGGCCTGGTGTCGAGGCTCTTTATCTCTCTCTGGAGCCGGCCACTGCGCTGG
CGGAATACCAGCAGTTCGACGACTTGCTGCCCCCGGGCCTGGTAGTGACCTACATGGTGAAGATCGATCCGGTGGTGGAT
TTTCGGGGCGGCCTGGATGAAGCGTGGAACTCCGCATGGGCCGAGTTCTATTGCGACTGGCGGAGCGTGGTCTTTCAGGA
AAAGCGCGAGCCGCCCTCCTGGGCGCTTGGTGAACAGGCCAGGGCCGCCGGAGCCAAGGGCATTCTCTTCCGTTCTTCAG
TGCTCAAGGAGGGATGCAACCTCGTCGTCTTCAACCGCACGTTGACCGACCAGGACCTCATCTCCATTCACGACCCCGGC
GGGGAATTGCCGCTCAATCAACTGTCCTGGCCACGTTCCTGA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12299.20 Da        Isoelectric Point: 9.2365

>AT57991 WP_083247246.1 NZ_CP013136:c5174321-5173983 [Herbaspirillum seropedicae]
MGSGRGPAFISPQRFAQLLHMDIQTLANSMLLPVNTLLHAPESAHLQVRLRDALRVIQAGLAVSGSVEPTLRWFKESPLQ
PFGQKTAQRLCAEGRSEDLLRYLQSMEAGFAG

Download         Length: 339 bp

>AT57991 NZ_CP013136:c5174321-5173983 [Herbaspirillum seropedicae]
CTGGGTTCGGGGCGCGGTCCCGCTTTCATCTCTCCACAGCGGTTCGCACAGCTGCTACACATGGATATCCAGACCTTGGC
CAACAGTATGCTGTTGCCGGTCAACACGCTCTTGCATGCACCCGAGTCGGCGCACCTGCAGGTGCGCTTGCGCGATGCGC
TAAGGGTGATTCAGGCAGGCCTTGCCGTGTCGGGCAGCGTGGAGCCCACGCTGCGCTGGTTCAAGGAGAGCCCCCTGCAG
CCGTTCGGGCAGAAGACCGCCCAGAGGCTGTGCGCCGAAGGCAGGTCCGAAGACCTCCTGCGCTATCTTCAATCCATGGA
AGCCGGATTTGCCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References