Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2480111..2480778 Replicon chromosome
Accession NZ_CP013136
Organism Herbaspirillum seropedicae strain AU14040

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag hsc_RS10955 Protein ID WP_069373897.1
Coordinates 2480362..2480778 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag hsc_RS10950 Protein ID WP_069373896.1
Coordinates 2480111..2480365 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
hsc_RS10940 2476748..2478352 - 1605 WP_069373894.1 L-aspartate oxidase -
hsc_RS10945 2478527..2479738 - 1212 WP_069373895.1 formate-dependent phosphoribosylglycinamide formyltransferase -
hsc_RS10950 2480111..2480365 + 255 WP_069373896.1 plasmid stabilization protein Antitoxin
hsc_RS10955 2480362..2480778 + 417 WP_069373897.1 type II toxin-antitoxin system VapC family toxin Toxin
hsc_RS10960 2480803..2481105 - 303 WP_013234202.1 hypothetical protein -
hsc_RS10965 2481107..2482462 - 1356 WP_069373898.1 DUF1446 domain-containing protein -
hsc_RS10970 2482505..2483806 - 1302 WP_069373899.1 citrate:proton symporter -
hsc_RS10975 2483991..2485004 + 1014 WP_069373900.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14915.20 Da        Isoelectric Point: 5.1150

>T57988 WP_069373897.1 NZ_CP013136:2480362-2480778 [Herbaspirillum seropedicae]
MIVLDTNVVSEAMKPAPDAAVQAWFNDQAPDTLYLTSITVAEIGFGIACLSAGRRQDLLARRFEGLLRMFKDRILPFDMD
AARSHAELAAMARRAGRGFPTPDGYIAAIAASCGFLVASRDVAPYLAAELTVINPWQA

Download         Length: 417 bp

>T57988 NZ_CP013136:2480362-2480778 [Herbaspirillum seropedicae]
ATGATCGTCCTGGATACCAACGTGGTGTCCGAGGCCATGAAGCCGGCCCCGGACGCCGCCGTACAGGCCTGGTTCAATGA
CCAGGCACCCGACACGCTCTACCTGACCAGCATTACGGTGGCCGAGATCGGCTTCGGCATAGCTTGCCTGTCTGCCGGCC
GTCGCCAGGATTTGCTGGCGCGTCGCTTCGAGGGCTTGCTGCGCATGTTCAAGGACCGCATCCTGCCCTTCGATATGGAC
GCCGCACGCTCGCATGCCGAGCTAGCCGCCATGGCCAGGCGTGCAGGCCGGGGATTTCCCACGCCGGATGGCTACATAGC
CGCCATTGCCGCTTCCTGCGGATTCCTCGTGGCGTCGCGCGATGTCGCCCCTTATCTGGCCGCAGAGCTGACGGTCATCA
ATCCCTGGCAAGCCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9274.53 Da        Isoelectric Point: 6.4677

>AT57988 WP_069373896.1 NZ_CP013136:2480111-2480365 [Herbaspirillum seropedicae]
MATVTVRNLPDEVHRALRVRAAQHGRSTEAEIREILTLAVRPAGQLRLGDALAAMSRELGLSNEDVEALQQTRERAPAQP
MSFE

Download         Length: 255 bp

>AT57988 NZ_CP013136:2480111-2480365 [Herbaspirillum seropedicae]
ATGGCCACCGTCACAGTCCGGAACCTCCCCGACGAGGTCCATCGTGCCCTGCGCGTGCGCGCGGCCCAGCATGGCCGCAG
CACCGAGGCGGAAATCCGCGAGATTCTCACCCTGGCAGTCAGGCCTGCCGGACAACTGCGCCTGGGAGACGCCCTGGCGG
CAATGAGCCGAGAGCTGGGTCTGAGCAATGAAGATGTCGAAGCCCTGCAGCAGACCCGCGAACGTGCGCCAGCCCAACCG
ATGAGTTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References