Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2151458..2152988 Replicon chromosome
Accession NZ_CP013127
Organism Bradyrhizobium diazoefficiens strain USDA 122

Toxin (Protein)


Gene name rlegT Uniprot ID A0A562QN92
Locus tag BD122_RS10170 Protein ID WP_018647871.1
Coordinates 2151458..2152378 (-) Length 307 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A810CIT3
Locus tag BD122_RS10175 Protein ID WP_026312796.1
Coordinates 2152368..2152988 (-) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BD122_RS10155 2147433..2147951 - 519 Protein_1938 exonuclease subunit SbcD -
BD122_RS10160 2147960..2150068 - 2109 WP_011084726.1 DUF87 domain-containing protein -
BD122_RS10165 2150076..2151380 - 1305 WP_028176022.1 SIR2 family protein -
BD122_RS10170 2151458..2152378 - 921 WP_018647871.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
BD122_RS10175 2152368..2152988 - 621 WP_026312796.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
BD122_RS10180 2153202..2153948 - 747 WP_018647872.1 DCL family protein -
BD122_RS10185 2153923..2156433 - 2511 WP_011084731.1 AAA family ATPase -
BD122_RS45485 2156396..2156623 - 228 WP_131234255.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-264)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-56)


Sequences

Toxin        


Download         Length: 307 a.a.        Molecular weight: 34027.14 Da        Isoelectric Point: 5.2727

>T57969 WP_018647871.1 NZ_CP013127:c2152378-2151458 [Bradyrhizobium diazoefficiens]
MAREPRNIGASVRARLLDRARAERSDFQILLTRYALERLLYRLSASPHRDRFILKGAMLFVTWIADPFRPTRDLDLLGHG
DRDTEAIAETFRAICAQPVVDDGVTFDVAALMATPIREELEYGGVRVRTTATIAGARIPIQVDIGFGDAITPAAVEIDYP
TLLDAPTPHLRAYPVETVVAEKFAALVTLGVANSRLKDFYDLWVISRTFELRRAALAEAIQRTFERRGTVLPSVVPVGLT
DEFAETWAAQWRAFLERDRMAAAPDAFAVTVADLRLFLMPLVVGLKEERIWPPSGPWSPGAAIDEA

Download         Length: 921 bp

>T57969 NZ_CP013127:c2152378-2151458 [Bradyrhizobium diazoefficiens]
ATGGCGCGTGAGCCTCGCAACATCGGCGCATCAGTGCGAGCGCGGCTCCTCGATCGGGCACGTGCCGAGCGATCGGACTT
CCAGATTCTCCTGACGCGATATGCGCTCGAGCGTCTGCTCTACCGGCTAAGCGCGTCGCCGCACCGCGACCGCTTCATCC
TCAAAGGTGCGATGCTCTTCGTGACCTGGATAGCCGATCCGTTTCGGCCTACGCGCGATCTGGATCTGCTTGGCCACGGC
GACCGCGACACCGAAGCCATTGCCGAAACCTTCCGGGCCATTTGTGCGCAGCCGGTCGTCGATGACGGTGTGACGTTTGA
TGTCGCAGCGCTGATGGCGACCCCGATTCGTGAGGAGCTGGAATATGGTGGCGTGCGGGTCCGCACAACGGCAACTATCG
CCGGGGCGCGTATTCCGATCCAGGTCGACATCGGTTTCGGCGACGCCATTACACCCGCGGCGGTCGAGATCGACTATCCC
ACCCTGCTGGACGCCCCAACGCCGCACCTTCGCGCATATCCGGTCGAAACAGTGGTAGCTGAGAAATTCGCAGCGCTCGT
GACGCTCGGCGTGGCCAACAGTCGGCTCAAGGATTTCTATGATCTCTGGGTAATCTCCCGAACATTCGAGCTTCGCCGGG
CCGCTCTTGCCGAGGCAATTCAGCGGACCTTCGAGCGACGCGGAACGGTCCTCCCATCCGTTGTCCCGGTCGGTCTGACC
GATGAATTCGCGGAAACATGGGCCGCCCAGTGGCGCGCCTTCCTGGAGCGCGATCGGATGGCAGCCGCACCGGATGCTTT
TGCCGTTACCGTCGCCGATCTCCGCCTCTTCTTGATGCCCCTGGTCGTCGGATTGAAAGAAGAACGAATTTGGCCGCCGA
GCGGGCCATGGTCGCCGGGAGCAGCAATCGATGAGGCATAG

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 23385.28 Da        Isoelectric Point: 10.0691

>AT57969 WP_026312796.1 NZ_CP013127:c2152988-2152368 [Bradyrhizobium diazoefficiens]
MPSTSAQRLRALDLLKTRGMLRLKDFIAEGIGPETLARLVREEAVVRPARGLYQLPDAHLEAAHTLAEAAVLVPKGVVCL
TSALQYHELTLQMPSAVWMAIDRSAWRPKIDYPPIRFVRFTGSALTEGIERHRIENVDVPITDPARTIVDCFRYRTKIGL
DVAMEGLREGLRRRRCKPDQLWHYARKARVWSVMRPYVEAMVSDGA

Download         Length: 621 bp

>AT57969 NZ_CP013127:c2152988-2152368 [Bradyrhizobium diazoefficiens]
ATGCCGTCCACCAGCGCCCAGCGACTTCGCGCGCTCGACCTCCTGAAGACCCGAGGAATGCTCCGGCTGAAGGATTTCAT
CGCCGAAGGCATCGGCCCGGAGACGCTTGCCCGTCTTGTTCGGGAGGAGGCAGTCGTCCGCCCAGCACGTGGGCTCTATC
AACTCCCCGACGCCCACCTCGAGGCTGCCCATACCCTCGCCGAGGCAGCAGTTCTGGTTCCAAAGGGTGTGGTCTGTCTT
ACCTCGGCCCTCCAATACCACGAACTGACGCTGCAGATGCCGTCGGCTGTATGGATGGCGATCGATCGCTCCGCCTGGCG
ACCCAAGATCGATTATCCACCTATCCGGTTCGTGCGATTCACCGGATCGGCGCTTACCGAAGGGATCGAGCGTCACCGCA
TTGAGAATGTCGACGTTCCTATCACGGATCCGGCGAGGACAATTGTCGATTGCTTTCGCTACCGAACCAAGATCGGCCTT
GACGTCGCGATGGAGGGGCTGCGCGAAGGCCTCCGCCGTCGCCGATGCAAGCCGGATCAACTCTGGCATTACGCTCGCAA
GGCGCGGGTCTGGTCGGTCATGCGTCCCTACGTCGAAGCAATGGTGTCCGATGGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A562QN92

Antitoxin

Source ID Structure
AlphaFold DB A0A810CIT3

References