Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prcAT/RES-Xre
Location 68293..69185 Replicon plasmid pPME5
Accession NZ_CP013125
Organism Pseudomonas mendocina S5.2

Toxin (Protein)


Gene name PrcT Uniprot ID -
Locus tag DW68_RS25605 Protein ID WP_075723462.1
Coordinates 68293..68751 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name PrcA Uniprot ID -
Locus tag DW68_RS24095 Protein ID WP_017362405.1
Coordinates 68748..69185 (-) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DW68_RS24045 63347..63988 + 642 WP_017362415.1 hypothetical protein -
DW68_RS24050 63990..64610 + 621 WP_017362414.1 hypothetical protein -
DW68_RS24055 64671..65102 + 432 WP_017362413.1 hypothetical protein -
DW68_RS24060 65113..65436 + 324 WP_017362412.1 hypothetical protein -
DW68_RS25815 65447..65653 + 207 WP_075723465.1 hypothetical protein -
DW68_RS24065 65836..66555 - 720 WP_017362411.1 NUDIX hydrolase -
DW68_RS24070 66558..67373 - 816 WP_017362410.1 hypothetical protein -
DW68_RS24085 67922..68296 - 375 WP_017362407.1 hypothetical protein -
DW68_RS25605 68293..68751 - 459 WP_075723462.1 RES family NAD+ phosphorylase Toxin
DW68_RS24095 68748..69185 - 438 WP_017362405.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
DW68_RS24100 69264..69815 - 552 WP_017362404.1 hypothetical protein -
DW68_RS24105 69991..70917 + 927 WP_017362403.1 ParA family protein -
DW68_RS24110 70914..72029 + 1116 WP_017362402.1 ParB N-terminal domain-containing protein -
DW68_RS24115 72026..72427 + 402 WP_017362401.1 hypothetical protein -
DW68_RS24120 72535..72921 + 387 WP_017362400.1 hypothetical protein -
DW68_RS24125 72973..73251 - 279 WP_036995125.1 hypothetical protein -
DW68_RS24130 73269..74054 - 786 WP_172825371.1 DUF2034 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..252328 252328


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(4-141)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(93-141)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17165.47 Da        Isoelectric Point: 5.5587

>T57962 WP_075723462.1 NZ_CP013125:c68751-68293 [Pseudomonas mendocina S5.2]
MSRKWRMSPFSDLSGRGGVIAQGRWHHAGRPVVYLTDSPSSAMLETLVHLEIDPEDLPNTFQLLQVDLPDHVSEQRVGTL
PTGWREDQEMTRKIGDEWLDGGESLILEVPSAIMPHTQNFLLNPQHPEAAEACVKAERYPFDTRLLKGALKR

Download         Length: 459 bp

>T57962 NZ_CP013125:c68751-68293 [Pseudomonas mendocina S5.2]
ATGAGCAGGAAGTGGCGCATGTCCCCGTTCTCCGACCTAAGCGGGCGTGGTGGTGTGATTGCACAGGGTAGGTGGCACCA
TGCAGGTCGCCCAGTGGTGTACCTCACAGACAGCCCGTCATCGGCCATGCTGGAGACTCTTGTTCATCTTGAGATTGATC
CAGAGGACCTGCCAAACACCTTCCAATTGCTTCAAGTTGATCTTCCTGATCACGTTTCCGAACAGCGCGTTGGCACTCTG
CCAACTGGTTGGAGGGAAGATCAGGAGATGACCCGGAAAATCGGAGATGAATGGCTCGATGGCGGAGAGTCCCTGATACT
CGAAGTCCCCAGCGCCATCATGCCTCATACCCAGAACTTCCTATTGAACCCTCAGCACCCGGAAGCTGCTGAAGCATGTG
TCAAAGCAGAGCGTTATCCATTTGACACGCGCCTCCTGAAAGGAGCGCTCAAGCGATGA

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 15856.99 Da        Isoelectric Point: 4.4463

>AT57962 WP_017362405.1 NZ_CP013125:c69185-68748 [Pseudomonas mendocina S5.2]
MAFTLRDGLPADAYAQYRLHLACLTGVPADTREDEAANLVDGGFDRAVLHLLLELSNPVPVRIPADDAQTDAPKYSPEFS
RTLYGIASGIALAFTVFGEKDKALRWLKKPKDRFEGRTPLDVLQDDEGQEQVITMLVQIGEGIGA

Download         Length: 438 bp

>AT57962 NZ_CP013125:c69185-68748 [Pseudomonas mendocina S5.2]
ATGGCTTTCACGTTGCGAGACGGACTTCCAGCCGACGCCTATGCGCAGTACCGGCTCCATCTTGCTTGCCTGACCGGTGT
TCCAGCCGATACCCGAGAGGACGAAGCTGCGAACCTGGTGGACGGTGGCTTTGACCGCGCAGTTCTGCACCTGCTGCTTG
AGCTTTCCAATCCAGTTCCGGTGCGTATCCCGGCCGATGACGCGCAGACTGACGCCCCCAAATATTCGCCGGAATTCAGT
CGAACCCTTTATGGCATCGCCAGCGGCATTGCTTTGGCTTTCACGGTTTTCGGCGAGAAAGATAAAGCCCTTCGCTGGCT
GAAGAAGCCAAAGGACCGATTTGAAGGAAGAACGCCACTCGATGTTCTTCAGGATGACGAAGGCCAAGAGCAAGTCATTA
CCATGCTGGTCCAGATTGGCGAAGGTATCGGTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References