Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
Location | 2747209..2748007 | Replicon | chromosome |
Accession | NZ_CP013112 | ||
Organism | Escherichia coli strain YD786 |
Toxin (Protein)
Gene name | yeeV | Uniprot ID | - |
Locus tag | ASE18_RS13560 | Protein ID | WP_057916008.1 |
Coordinates | 2747630..2748007 (+) | Length | 126 a.a. |
Antitoxin (Protein)
Gene name | yeeU | Uniprot ID | A0A1L4NTN5 |
Locus tag | ASE18_RS13555 | Protein ID | WP_001605875.1 |
Coordinates | 2747209..2747583 (+) | Length | 125 a.a. |
Genomic Context
Location: 2744400..2744630 (231 bp)
Type: Others
Protein ID: Protein_2583
Type: Others
Protein ID: Protein_2583
Location: 2744958..2745776 (819 bp)
Type: Others
Protein ID: WP_001234393.1
Type: Others
Protein ID: WP_001234393.1
Location: 2745868..2746353 (486 bp)
Type: Others
Protein ID: WP_001536436.1
Type: Others
Protein ID: WP_001536436.1
Location: 2746369..2746845 (477 bp)
Type: Others
Protein ID: WP_057916007.1
Type: Others
Protein ID: WP_057916007.1
Location: 2746914..2747135 (222 bp)
Type: Others
Protein ID: WP_000692303.1
Type: Others
Protein ID: WP_000692303.1
Location: 2747209..2747583 (375 bp)
Type: Antitoxin
Protein ID: WP_001605875.1
Type: Antitoxin
Protein ID: WP_001605875.1
Location: 2747630..2748007 (378 bp)
Type: Toxin
Protein ID: WP_057916008.1
Type: Toxin
Protein ID: WP_057916008.1
Location: 2748004..2748153 (150 bp)
Type: Others
Protein ID: Protein_2590
Type: Others
Protein ID: Protein_2590
Location: 2748229..2748426 (198 bp)
Type: Others
Protein ID: WP_023563519.1
Type: Others
Protein ID: WP_023563519.1
Location: 2748511..2749353 (843 bp)
Type: Others
Protein ID: WP_057916009.1
Type: Others
Protein ID: WP_057916009.1
Location: 2749634..2750170 (537 bp)
Type: Others
Protein ID: WP_000942786.1
Type: Others
Protein ID: WP_000942786.1
Location: 2750172..2751350 (1179 bp)
Type: Others
Protein ID: WP_000094970.1
Type: Others
Protein ID: WP_000094970.1
Location: 2751347..2752324 (978 bp)
Type: Others
Protein ID: WP_000633220.1
Type: Others
Protein ID: WP_000633220.1
Location: 2752327..2752530 (204 bp)
Type: Others
Protein ID: Protein_2596
Type: Others
Protein ID: Protein_2596
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ASE18_RS25120 | 2744400..2744630 | + | 231 | Protein_2583 | autotransporter domain-containing protein | - |
ASE18_RS13535 | 2744958..2745776 | + | 819 | WP_001234393.1 | DUF945 domain-containing protein | - |
ASE18_RS13540 | 2745868..2746353 | + | 486 | WP_001536436.1 | antirestriction protein | - |
ASE18_RS13545 | 2746369..2746845 | + | 477 | WP_057916007.1 | RadC family protein | - |
ASE18_RS13550 | 2746914..2747135 | + | 222 | WP_000692303.1 | DUF987 domain-containing protein | - |
ASE18_RS13555 | 2747209..2747583 | + | 375 | WP_001605875.1 | type IV toxin-antitoxin system toxin CbtA | Antitoxin |
ASE18_RS13560 | 2747630..2748007 | + | 378 | WP_057916008.1 | TA system toxin CbtA family protein | Toxin |
ASE18_RS26935 | 2748004..2748153 | + | 150 | Protein_2590 | hypothetical protein | - |
ASE18_RS26940 | 2748229..2748426 | + | 198 | WP_023563519.1 | DUF957 domain-containing protein | - |
ASE18_RS13575 | 2748511..2749353 | + | 843 | WP_057916009.1 | DUF4942 domain-containing protein | - |
ASE18_RS13580 | 2749634..2750170 | - | 537 | WP_000942786.1 | GspM family type II secretion system protein YghD | - |
ASE18_RS13585 | 2750172..2751350 | - | 1179 | WP_000094970.1 | type II secretion system protein GspL | - |
ASE18_RS13590 | 2751347..2752324 | - | 978 | WP_000633220.1 | type II secretion system minor pseudopilin GspK | - |
ASE18_RS13595 | 2752327..2752530 | - | 204 | Protein_2596 | type II secretion system protein GspJ | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 14140.14 Da Isoelectric Point: 7.2652
>T57934 WP_057916008.1 NZ_CP013112:2747630-2748007 [Escherichia coli]
MKTLPDTHVREASCCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SACTRSQLINSIDILRARRATSLMTRDNYRTVNNITLGKHPEAKQ
MKTLPDTHVREASCCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SACTRSQLINSIDILRARRATSLMTRDNYRTVNNITLGKHPEAKQ
Download Length: 378 bp
>T57934 NZ_CP013112:2747630-2748007 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCAGCCTGATGACCCGCGA
CAATTACCGAACAGTAAATAACATTACTCTGGGTAAGCATCCGGAGGCGAAACAATGA
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCAGCCTGATGACCCGCGA
CAATTACCGAACAGTAAATAACATTACTCTGGGTAAGCATCCGGAGGCGAAACAATGA
Antitoxin
Download Length: 125 a.a. Molecular weight: 13594.42 Da Isoelectric Point: 5.4554
>AT57934 WP_001605875.1 NZ_CP013112:2747209-2747583 [Escherichia coli]
VSDTLPGTTLPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLACEADTLGSCGYVYMAVYPTLAPATTS
VSDTLPGTTLPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLACEADTLGSCGYVYMAVYPTLAPATTS
Download Length: 375 bp
>AT57934 NZ_CP013112:2747209-2747583 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGGCCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGGCCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1L4NTN5 |