Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 3358081..3358721 | Replicon | chromosome |
Accession | NZ_CP013106 | ||
Organism | Halomonas huangheensis strain BJGMM-B45 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | - |
Locus tag | AR456_RS14535 | Protein ID | WP_021818632.1 |
Coordinates | 3358081..3358494 (-) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | - |
Locus tag | AR456_RS14540 | Protein ID | WP_031207572.1 |
Coordinates | 3358491..3358721 (-) | Length | 77 a.a. |
Genomic Context
Location: 3355835..3356179 (345 bp)
Type: Others
Protein ID: WP_021818635.1
Type: Others
Protein ID: WP_021818635.1
Location: 3356312..3357193 (882 bp)
Type: Others
Protein ID: WP_021818634.1
Type: Others
Protein ID: WP_021818634.1
Location: 3357186..3357974 (789 bp)
Type: Others
Protein ID: WP_021818633.1
Type: Others
Protein ID: WP_021818633.1
Location: 3359561..3360166 (606 bp)
Type: Others
Protein ID: WP_021818629.1
Type: Others
Protein ID: WP_021818629.1
Location: 3360163..3360912 (750 bp)
Type: Others
Protein ID: WP_021818628.1
Type: Others
Protein ID: WP_021818628.1
Location: 3361035..3361466 (432 bp)
Type: Others
Protein ID: WP_021818627.1
Type: Others
Protein ID: WP_021818627.1
Location: 3362313..3363596 (1284 bp)
Type: Others
Protein ID: WP_031207570.1
Type: Others
Protein ID: WP_031207570.1
Location: 3353344..3354813 (1470 bp)
Type: Others
Protein ID: WP_021818637.1
Type: Others
Protein ID: WP_021818637.1
Location: 3354825..3355520 (696 bp)
Type: Others
Protein ID: WP_021818636.1
Type: Others
Protein ID: WP_021818636.1
Location: 3358081..3358494 (414 bp)
Type: Toxin
Protein ID: WP_021818632.1
Type: Toxin
Protein ID: WP_021818632.1
Location: 3358491..3358721 (231 bp)
Type: Antitoxin
Protein ID: WP_031207572.1
Type: Antitoxin
Protein ID: WP_031207572.1
Location: 3358979..3359335 (357 bp)
Type: Others
Protein ID: WP_021818630.1
Type: Others
Protein ID: WP_021818630.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AR456_RS14510 | 3353344..3354813 | - | 1470 | WP_021818637.1 | HAMP domain-containing histidine kinase | - |
AR456_RS14515 | 3354825..3355520 | - | 696 | WP_021818636.1 | response regulator transcription factor | - |
AR456_RS14520 | 3355835..3356179 | + | 345 | WP_021818635.1 | hypothetical protein | - |
AR456_RS14525 | 3356312..3357193 | + | 882 | WP_021818634.1 | cytochrome b/b6 domain-containing protein | - |
AR456_RS14530 | 3357186..3357974 | + | 789 | WP_021818633.1 | molybdopterin-binding protein | - |
AR456_RS14535 | 3358081..3358494 | - | 414 | WP_021818632.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
AR456_RS14540 | 3358491..3358721 | - | 231 | WP_031207572.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
AR456_RS14545 | 3358979..3359335 | - | 357 | WP_021818630.1 | nucleotide pyrophosphohydrolase | - |
AR456_RS14550 | 3359561..3360166 | + | 606 | WP_021818629.1 | sigma-70 family RNA polymerase sigma factor | - |
AR456_RS14555 | 3360163..3360912 | + | 750 | WP_021818628.1 | anti-sigma factor | - |
AR456_RS14560 | 3361035..3361466 | + | 432 | WP_021818627.1 | hypothetical protein | - |
AR456_RS14565 | 3362313..3363596 | + | 1284 | WP_031207570.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 15204.54 Da Isoelectric Point: 6.2195
>T57915 WP_021818632.1 NZ_CP013106:c3358494-3358081 [Halomonas huangheensis]
MTCYMLDTCICSFIMREHPIAVIQRLADEAEQGSRIVVSAITYAEMRYGQIGKKASTKHKVLVDEFVRRLDAVLAWDQRA
VDATVEVMRELRIAGTPIGPNDTAIAGHAISAGCTLVTNNVREFGRVPSLVYEDWCS
MTCYMLDTCICSFIMREHPIAVIQRLADEAEQGSRIVVSAITYAEMRYGQIGKKASTKHKVLVDEFVRRLDAVLAWDQRA
VDATVEVMRELRIAGTPIGPNDTAIAGHAISAGCTLVTNNVREFGRVPSLVYEDWCS
Download Length: 414 bp
>T57915 NZ_CP013106:c3358494-3358081 [Halomonas huangheensis]
ATGACCTGCTATATGCTCGATACCTGTATTTGTTCCTTCATCATGCGGGAGCATCCTATTGCGGTGATTCAGCGGTTGGC
TGATGAGGCTGAGCAGGGCAGCCGGATTGTTGTCTCGGCCATTACTTATGCCGAGATGCGTTACGGCCAGATAGGCAAAA
AGGCCTCTACCAAGCACAAGGTACTAGTGGACGAGTTTGTGAGACGACTTGATGCTGTGCTGGCATGGGACCAGAGGGCG
GTGGACGCGACGGTAGAGGTCATGCGCGAGCTACGTATTGCTGGCACTCCCATTGGGCCCAATGATACGGCGATAGCGGG
TCATGCAATCTCTGCTGGTTGTACGCTGGTAACCAATAACGTGCGTGAATTTGGTCGCGTTCCGAGCCTTGTATACGAAG
ACTGGTGCTCTTGA
ATGACCTGCTATATGCTCGATACCTGTATTTGTTCCTTCATCATGCGGGAGCATCCTATTGCGGTGATTCAGCGGTTGGC
TGATGAGGCTGAGCAGGGCAGCCGGATTGTTGTCTCGGCCATTACTTATGCCGAGATGCGTTACGGCCAGATAGGCAAAA
AGGCCTCTACCAAGCACAAGGTACTAGTGGACGAGTTTGTGAGACGACTTGATGCTGTGCTGGCATGGGACCAGAGGGCG
GTGGACGCGACGGTAGAGGTCATGCGCGAGCTACGTATTGCTGGCACTCCCATTGGGCCCAATGATACGGCGATAGCGGG
TCATGCAATCTCTGCTGGTTGTACGCTGGTAACCAATAACGTGCGTGAATTTGGTCGCGTTCCGAGCCTTGTATACGAAG
ACTGGTGCTCTTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8506.61 Da Isoelectric Point: 4.5702
>AT57915 WP_031207572.1 NZ_CP013106:c3358721-3358491 [Halomonas huangheensis]
MRTVSIFKNGKNQAVRLPADMAYEGVGELEISREGDVITLRPARPSWLSLPEFSKADADFLEERPVVVSDEGRFNP
MRTVSIFKNGKNQAVRLPADMAYEGVGELEISREGDVITLRPARPSWLSLPEFSKADADFLEERPVVVSDEGRFNP
Download Length: 231 bp
>AT57915 NZ_CP013106:c3358721-3358491 [Halomonas huangheensis]
ATGCGTACTGTATCCATTTTCAAGAATGGCAAGAACCAGGCTGTCCGTCTGCCAGCAGATATGGCCTATGAAGGCGTTGG
GGAGCTGGAAATTTCGCGAGAAGGCGATGTCATCACTCTTCGGCCTGCCCGGCCTTCCTGGCTATCTCTTCCTGAGTTCT
CGAAAGCTGATGCTGACTTCCTGGAAGAGCGACCTGTTGTTGTCAGTGATGAAGGCAGGTTCAATCCATGA
ATGCGTACTGTATCCATTTTCAAGAATGGCAAGAACCAGGCTGTCCGTCTGCCAGCAGATATGGCCTATGAAGGCGTTGG
GGAGCTGGAAATTTCGCGAGAAGGCGATGTCATCACTCTTCGGCCTGCCCGGCCTTCCTGGCTATCTCTTCCTGAGTTCT
CGAAAGCTGATGCTGACTTCCTGGAAGAGCGACCTGTTGTTGTCAGTGATGAAGGCAGGTTCAATCCATGA