Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3358081..3358721 Replicon chromosome
Accession NZ_CP013106
Organism Halomonas huangheensis strain BJGMM-B45

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag AR456_RS14535 Protein ID WP_021818632.1
Coordinates 3358081..3358494 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag AR456_RS14540 Protein ID WP_031207572.1
Coordinates 3358491..3358721 (-) Length 77 a.a.

Genomic Context


AR456_RS14520AR456_RS14525AR456_RS14530AR456_RS14550AR456_RS14555AR456_RS14560AR456_RS14565AR456_RS14510AR456_RS14515AR456_RS14535AR456_RS14540AR456_RS14545
Location: 3355835..3356179 (345 bp)
Type: Others
Protein ID: WP_021818635.1
Location: 3356312..3357193 (882 bp)
Type: Others
Protein ID: WP_021818634.1
Location: 3357186..3357974 (789 bp)
Type: Others
Protein ID: WP_021818633.1
Location: 3359561..3360166 (606 bp)
Type: Others
Protein ID: WP_021818629.1
Location: 3360163..3360912 (750 bp)
Type: Others
Protein ID: WP_021818628.1
Location: 3361035..3361466 (432 bp)
Type: Others
Protein ID: WP_021818627.1
Location: 3362313..3363596 (1284 bp)
Type: Others
Protein ID: WP_031207570.1
Location: 3353344..3354813 (1470 bp)
Type: Others
Protein ID: WP_021818637.1
Location: 3354825..3355520 (696 bp)
Type: Others
Protein ID: WP_021818636.1
Location: 3358081..3358494 (414 bp)
Type: Toxin
Protein ID: WP_021818632.1
Location: 3358491..3358721 (231 bp)
Type: Antitoxin
Protein ID: WP_031207572.1
Location: 3358979..3359335 (357 bp)
Type: Others
Protein ID: WP_021818630.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AR456_RS145103353344..3354813-1470WP_021818637.1HAMP domain-containing histidine kinase-
AR456_RS145153354825..3355520-696WP_021818636.1response regulator transcription factor-
AR456_RS145203355835..3356179+345WP_021818635.1hypothetical protein-
AR456_RS145253356312..3357193+882WP_021818634.1cytochrome b/b6 domain-containing protein-
AR456_RS145303357186..3357974+789WP_021818633.1molybdopterin-binding protein-
AR456_RS145353358081..3358494-414WP_021818632.1type II toxin-antitoxin system VapC family toxinToxin
AR456_RS145403358491..3358721-231WP_031207572.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
AR456_RS145453358979..3359335-357WP_021818630.1nucleotide pyrophosphohydrolase-
AR456_RS145503359561..3360166+606WP_021818629.1sigma-70 family RNA polymerase sigma factor-
AR456_RS145553360163..3360912+750WP_021818628.1anti-sigma factor-
AR456_RS145603361035..3361466+432WP_021818627.1hypothetical protein-
AR456_RS145653362313..3363596+1284WP_031207570.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-127)

Antitoxin

(7-51)


Sequences


Toxin        


Download         Length: 138 a.a.        Molecular weight: 15204.54 Da        Isoelectric Point: 6.2195

>T57915 WP_021818632.1 NZ_CP013106:c3358494-3358081 [Halomonas huangheensis]
MTCYMLDTCICSFIMREHPIAVIQRLADEAEQGSRIVVSAITYAEMRYGQIGKKASTKHKVLVDEFVRRLDAVLAWDQRA
VDATVEVMRELRIAGTPIGPNDTAIAGHAISAGCTLVTNNVREFGRVPSLVYEDWCS

Download         Length: 414 bp

>T57915 NZ_CP013106:c3358494-3358081 [Halomonas huangheensis]
ATGACCTGCTATATGCTCGATACCTGTATTTGTTCCTTCATCATGCGGGAGCATCCTATTGCGGTGATTCAGCGGTTGGC
TGATGAGGCTGAGCAGGGCAGCCGGATTGTTGTCTCGGCCATTACTTATGCCGAGATGCGTTACGGCCAGATAGGCAAAA
AGGCCTCTACCAAGCACAAGGTACTAGTGGACGAGTTTGTGAGACGACTTGATGCTGTGCTGGCATGGGACCAGAGGGCG
GTGGACGCGACGGTAGAGGTCATGCGCGAGCTACGTATTGCTGGCACTCCCATTGGGCCCAATGATACGGCGATAGCGGG
TCATGCAATCTCTGCTGGTTGTACGCTGGTAACCAATAACGTGCGTGAATTTGGTCGCGTTCCGAGCCTTGTATACGAAG
ACTGGTGCTCTTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8506.61 Da        Isoelectric Point: 4.5702

>AT57915 WP_031207572.1 NZ_CP013106:c3358721-3358491 [Halomonas huangheensis]
MRTVSIFKNGKNQAVRLPADMAYEGVGELEISREGDVITLRPARPSWLSLPEFSKADADFLEERPVVVSDEGRFNP

Download         Length: 231 bp

>AT57915 NZ_CP013106:c3358721-3358491 [Halomonas huangheensis]
ATGCGTACTGTATCCATTTTCAAGAATGGCAAGAACCAGGCTGTCCGTCTGCCAGCAGATATGGCCTATGAAGGCGTTGG
GGAGCTGGAAATTTCGCGAGAAGGCGATGTCATCACTCTTCGGCCTGCCCGGCCTTCCTGGCTATCTCTTCCTGAGTTCT
CGAAAGCTGATGCTGACTTCCTGGAAGAGCGACCTGTTGTTGTCAGTGATGAAGGCAGGTTCAATCCATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References