Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-StbC |
| Location | 2566801..2567461 | Replicon | chromosome |
| Accession | NZ_CP013102 | ||
| Organism | Paraburkholderia caribensis strain MWAP64 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | AN416_RS11335 | Protein ID | WP_082434037.1 |
| Coordinates | 2566801..2567229 (-) | Length | 143 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | AN416_RS11340 | Protein ID | WP_060602697.1 |
| Coordinates | 2567216..2567461 (-) | Length | 82 a.a. |
Genomic Context
Location: 2564376..2565014 (639 bp)
Type: Others
Protein ID: WP_054934557.1
Type: Others
Protein ID: WP_054934557.1
Location: 2567631..2568251 (621 bp)
Type: Others
Protein ID: WP_060601137.1
Type: Others
Protein ID: WP_060601137.1
Location: 2571356..2571868 (513 bp)
Type: Others
Protein ID: WP_060601139.1
Type: Others
Protein ID: WP_060601139.1
Location: 2562869..2563825 (957 bp)
Type: Others
Protein ID: WP_054934558.1
Type: Others
Protein ID: WP_054934558.1
Location: 2565057..2566034 (978 bp)
Type: Others
Protein ID: WP_054934556.1
Type: Others
Protein ID: WP_054934556.1
Location: 2566239..2566712 (474 bp)
Type: Others
Protein ID: WP_060601133.1
Type: Others
Protein ID: WP_060601133.1
Location: 2566801..2567229 (429 bp)
Type: Toxin
Protein ID: WP_082434037.1
Type: Toxin
Protein ID: WP_082434037.1
Location: 2567216..2567461 (246 bp)
Type: Antitoxin
Protein ID: WP_060602697.1
Type: Antitoxin
Protein ID: WP_060602697.1
Location: 2568413..2569510 (1098 bp)
Type: Others
Protein ID: WP_035990998.1
Type: Others
Protein ID: WP_035990998.1
Location: 2569718..2570182 (465 bp)
Type: Others
Protein ID: WP_035990996.1
Type: Others
Protein ID: WP_035990996.1
Location: 2570319..2571203 (885 bp)
Type: Others
Protein ID: WP_054934550.1
Type: Others
Protein ID: WP_054934550.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AN416_RS11315 | 2562869..2563825 | - | 957 | WP_054934558.1 | sugar ABC transporter substrate-binding protein | - |
| AN416_RS11320 | 2564376..2565014 | + | 639 | WP_054934557.1 | LysE family translocator | - |
| AN416_RS11325 | 2565057..2566034 | - | 978 | WP_054934556.1 | magnesium/cobalt transporter CorA | - |
| AN416_RS11330 | 2566239..2566712 | - | 474 | WP_060601133.1 | hypothetical protein | - |
| AN416_RS11335 | 2566801..2567229 | - | 429 | WP_082434037.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| AN416_RS11340 | 2567216..2567461 | - | 246 | WP_060602697.1 | hypothetical protein | Antitoxin |
| AN416_RS11345 | 2567631..2568251 | + | 621 | WP_060601137.1 | ATP-binding protein | - |
| AN416_RS11350 | 2568413..2569510 | - | 1098 | WP_035990998.1 | saccharopine dehydrogenase NADP-binding domain-containing protein | - |
| AN416_RS11355 | 2569718..2570182 | - | 465 | WP_035990996.1 | Lrp/AsnC family transcriptional regulator | - |
| AN416_RS11360 | 2570319..2571203 | - | 885 | WP_054934550.1 | LysR family transcriptional regulator | - |
| AN416_RS11365 | 2571356..2571868 | + | 513 | WP_060601139.1 | Spy/CpxP family protein refolding chaperone | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 143 a.a. Molecular weight: 15715.91 Da Isoelectric Point: 7.4682
>T57911 WP_082434037.1 NZ_CP013102:c2567229-2566801 [Paraburkholderia caribensis]
VYLIDTNVISEMRKSSRANPGVQAFFETAKEGGHRLYLSVVTVGELRRGVDLIRHRGDKFQALRLEGWLDTIMNSFSSHI
LNVGTDVAQTWGHLRVPDPGHSLDKLIAATALIYNLTVVTRNVADFDGTGARVLNPFQLLDA
VYLIDTNVISEMRKSSRANPGVQAFFETAKEGGHRLYLSVVTVGELRRGVDLIRHRGDKFQALRLEGWLDTIMNSFSSHI
LNVGTDVAQTWGHLRVPDPGHSLDKLIAATALIYNLTVVTRNVADFDGTGARVLNPFQLLDA
Download Length: 429 bp
>T57911 NZ_CP013102:c2567229-2566801 [Paraburkholderia caribensis]
GTGTATTTGATTGATACCAATGTAATCAGCGAAATGCGCAAGAGCAGCCGCGCCAATCCGGGCGTACAGGCTTTTTTCGA
AACGGCGAAGGAAGGCGGGCATCGCCTGTATCTGTCTGTGGTGACGGTTGGCGAGTTGCGGCGCGGCGTCGACCTGATCC
GGCATCGGGGCGACAAGTTCCAGGCATTGCGCCTGGAAGGCTGGCTCGACACGATCATGAATTCGTTCAGCAGCCACATC
TTGAATGTCGGCACCGACGTTGCGCAGACGTGGGGCCATCTGCGCGTGCCCGACCCCGGGCATTCGCTGGACAAACTGAT
CGCGGCCACGGCCCTGATCTACAACCTGACTGTCGTGACGCGCAACGTGGCAGACTTCGATGGCACGGGCGCACGGGTGC
TCAATCCGTTCCAGCTTCTCGACGCATGA
GTGTATTTGATTGATACCAATGTAATCAGCGAAATGCGCAAGAGCAGCCGCGCCAATCCGGGCGTACAGGCTTTTTTCGA
AACGGCGAAGGAAGGCGGGCATCGCCTGTATCTGTCTGTGGTGACGGTTGGCGAGTTGCGGCGCGGCGTCGACCTGATCC
GGCATCGGGGCGACAAGTTCCAGGCATTGCGCCTGGAAGGCTGGCTCGACACGATCATGAATTCGTTCAGCAGCCACATC
TTGAATGTCGGCACCGACGTTGCGCAGACGTGGGGCCATCTGCGCGTGCCCGACCCCGGGCATTCGCTGGACAAACTGAT
CGCGGCCACGGCCCTGATCTACAACCTGACTGTCGTGACGCGCAACGTGGCAGACTTCGATGGCACGGGCGCACGGGTGC
TCAATCCGTTCCAGCTTCTCGACGCATGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8910.88 Da Isoelectric Point: 4.2208
>AT57911 WP_060602697.1 NZ_CP013102:c2567461-2567216 [Paraburkholderia caribensis]
MANLLVRNLDDALVQNLREQAAAHGRSVEAEHREILAQALFQPKKLSFAELLMSMPDVGDDADFERRNDATDDSGGPGVF
D
MANLLVRNLDDALVQNLREQAAAHGRSVEAEHREILAQALFQPKKLSFAELLMSMPDVGDDADFERRNDATDDSGGPGVF
D
Download Length: 246 bp
>AT57911 NZ_CP013102:c2567461-2567216 [Paraburkholderia caribensis]
ATGGCAAATCTTTTGGTCCGAAATCTGGACGATGCGTTGGTGCAGAACCTGCGTGAGCAGGCCGCGGCTCACGGGCGCAG
CGTCGAAGCAGAGCATCGGGAAATCCTGGCGCAGGCGCTCTTTCAGCCCAAGAAGCTCAGCTTTGCGGAATTGCTGATGA
GCATGCCCGACGTCGGCGACGACGCCGACTTCGAGCGCCGCAATGACGCAACTGACGATAGCGGGGGACCGGGTGTATTT
GATTGA
ATGGCAAATCTTTTGGTCCGAAATCTGGACGATGCGTTGGTGCAGAACCTGCGTGAGCAGGCCGCGGCTCACGGGCGCAG
CGTCGAAGCAGAGCATCGGGAAATCCTGGCGCAGGCGCTCTTTCAGCCCAAGAAGCTCAGCTTTGCGGAATTGCTGATGA
GCATGCCCGACGTCGGCGACGACGCCGACTTCGAGCGCCGCAATGACGCAACTGACGATAGCGGGGGACCGGGTGTATTT
GATTGA