Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4653909..4654939 | Replicon | chromosome |
| Accession | NZ_CP013068 | ||
| Organism | Pannonibacter phragmitetus strain 31801 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | A0A0U3PC36 |
| Locus tag | APZ00_RS21190 | Protein ID | WP_058900142.1 |
| Coordinates | 4653909..4654478 (-) | Length | 190 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | A0A0L0IUA3 |
| Locus tag | APZ00_RS21195 | Protein ID | WP_050474753.1 |
| Coordinates | 4654475..4654939 (-) | Length | 155 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| APZ00_RS21160 | 4650062..4650511 | - | 450 | WP_058900138.1 | GNAT family N-acetyltransferase | - |
| APZ00_RS21165 | 4650537..4650983 | - | 447 | WP_058900139.1 | PaaI family thioesterase | - |
| APZ00_RS21170 | 4651010..4651408 | - | 399 | WP_058900140.1 | MerR family DNA-binding transcriptional regulator | - |
| APZ00_RS21175 | 4651500..4652915 | - | 1416 | WP_058900141.1 | magnesium transporter | - |
| APZ00_RS21180 | 4653147..4653464 | - | 318 | WP_050474725.1 | YARHG domain-containing protein | - |
| APZ00_RS21190 | 4653909..4654478 | - | 570 | WP_058900142.1 | PIN domain-containing protein | Toxin |
| APZ00_RS21195 | 4654475..4654939 | - | 465 | WP_050474753.1 | helix-turn-helix domain-containing protein | Antitoxin |
| APZ00_RS26060 | 4655086..4655310 | + | 225 | WP_082676176.1 | pentapeptide repeat-containing protein | - |
| APZ00_RS21200 | 4655249..4655515 | - | 267 | WP_050474723.1 | flagellar motor switch protein FliN | - |
| APZ00_RS21205 | 4655659..4656387 | + | 729 | WP_058900143.1 | lipoyl(octanoyl) transferase LipB | - |
| APZ00_RS21210 | 4656544..4658559 | + | 2016 | WP_208991374.1 | 5'-nucleotidase C-terminal domain-containing protein | - |
| APZ00_RS21215 | 4658861..4659505 | + | 645 | WP_058900145.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21065.41 Da Isoelectric Point: 6.3324
>T57863 WP_058900142.1 NZ_CP013068:c4654478-4653909 [Pannonibacter phragmitetus]
VSQARVLLDANVLYPAPLRDLLPQLAVSDVVIAAWTERIHCEWIEALLRRQPWCERRALERTRDLMNEAISDCLIRGYEK
IIPSLVLPDPDDRHVLAAAIAGRCGVILTHNTRDFPPEALAPHGIEAQNPDEFLLAHLSRVPGLFCAAVKKVRSRLKTPP
LDPDEYLAVLRRQGLIETAAGLETFASSI
VSQARVLLDANVLYPAPLRDLLPQLAVSDVVIAAWTERIHCEWIEALLRRQPWCERRALERTRDLMNEAISDCLIRGYEK
IIPSLVLPDPDDRHVLAAAIAGRCGVILTHNTRDFPPEALAPHGIEAQNPDEFLLAHLSRVPGLFCAAVKKVRSRLKTPP
LDPDEYLAVLRRQGLIETAAGLETFASSI
Download Length: 570 bp
>T57863 NZ_CP013068:c4654478-4653909 [Pannonibacter phragmitetus]
GTGAGTCAGGCTCGGGTTTTGCTCGACGCAAATGTTCTTTACCCGGCCCCACTGCGGGATCTGTTGCCCCAGCTTGCCGT
TTCGGACGTTGTTATTGCGGCATGGACCGAACGCATACACTGCGAGTGGATTGAGGCGCTGTTGCGCAGGCAGCCGTGGT
GCGAGCGCCGGGCGCTTGAGCGGACAAGGGACCTTATGAATGAGGCAATAAGCGACTGCCTCATTCGTGGATACGAGAAA
ATTATCCCCTCGCTTGTCTTGCCTGACCCGGATGACCGCCATGTGCTTGCGGCGGCGATTGCCGGGCGCTGTGGCGTTAT
CCTGACACATAACACCAGGGATTTTCCGCCAGAGGCGCTGGCTCCTCATGGCATTGAAGCGCAAAATCCGGACGAGTTCC
TGCTCGCGCACCTTTCTCGTGTGCCGGGACTGTTCTGCGCCGCAGTGAAAAAAGTGCGGTCACGCCTGAAGACGCCGCCG
CTGGATCCTGATGAATATCTGGCTGTTCTGAGGCGTCAGGGGCTGATCGAAACGGCAGCCGGACTGGAGACCTTTGCCAG
CTCGATCTGA
GTGAGTCAGGCTCGGGTTTTGCTCGACGCAAATGTTCTTTACCCGGCCCCACTGCGGGATCTGTTGCCCCAGCTTGCCGT
TTCGGACGTTGTTATTGCGGCATGGACCGAACGCATACACTGCGAGTGGATTGAGGCGCTGTTGCGCAGGCAGCCGTGGT
GCGAGCGCCGGGCGCTTGAGCGGACAAGGGACCTTATGAATGAGGCAATAAGCGACTGCCTCATTCGTGGATACGAGAAA
ATTATCCCCTCGCTTGTCTTGCCTGACCCGGATGACCGCCATGTGCTTGCGGCGGCGATTGCCGGGCGCTGTGGCGTTAT
CCTGACACATAACACCAGGGATTTTCCGCCAGAGGCGCTGGCTCCTCATGGCATTGAAGCGCAAAATCCGGACGAGTTCC
TGCTCGCGCACCTTTCTCGTGTGCCGGGACTGTTCTGCGCCGCAGTGAAAAAAGTGCGGTCACGCCTGAAGACGCCGCCG
CTGGATCCTGATGAATATCTGGCTGTTCTGAGGCGTCAGGGGCTGATCGAAACGGCAGCCGGACTGGAGACCTTTGCCAG
CTCGATCTGA
Antitoxin
Download Length: 155 a.a. Molecular weight: 17061.75 Da Isoelectric Point: 8.0758
>AT57863 WP_050474753.1 NZ_CP013068:c4654939-4654475 [Pannonibacter phragmitetus]
VTFPVYSQRRPTRQEAAVARVSEQALACHARDGAPLKLRVTGHEETEVVELPAGAVTLLMEILKAMAAGQGVTVVPDDAE
LTTVQAAELLNVSRPFLIKLLEEGKIPHRKVGKHRRALMQDVIAYKRIMDRRREEILDQLVAEAQEQGMGYGAR
VTFPVYSQRRPTRQEAAVARVSEQALACHARDGAPLKLRVTGHEETEVVELPAGAVTLLMEILKAMAAGQGVTVVPDDAE
LTTVQAAELLNVSRPFLIKLLEEGKIPHRKVGKHRRALMQDVIAYKRIMDRRREEILDQLVAEAQEQGMGYGAR
Download Length: 465 bp
>AT57863 NZ_CP013068:c4654939-4654475 [Pannonibacter phragmitetus]
GTGACATTCCCGGTATACAGTCAGCGCAGGCCCACCCGGCAGGAGGCAGCGGTTGCACGCGTTTCCGAGCAGGCCCTTGC
CTGCCACGCGCGTGACGGAGCGCCGCTGAAATTGCGCGTAACGGGGCACGAAGAGACAGAGGTGGTGGAACTGCCGGCAG
GCGCAGTTACTCTGCTGATGGAAATTCTCAAGGCCATGGCAGCGGGGCAGGGGGTGACGGTTGTTCCCGATGATGCCGAG
TTGACCACGGTACAGGCTGCAGAGCTTCTGAATGTGTCCCGGCCCTTCCTGATCAAGCTCCTGGAGGAAGGTAAAATTCC
CCATCGCAAGGTCGGGAAGCACCGGCGGGCGCTCATGCAGGACGTGATTGCTTACAAGCGCATCATGGATCGCAGGCGGG
AGGAAATCCTCGACCAACTGGTTGCCGAAGCGCAGGAACAGGGCATGGGATACGGCGCAAGGTGA
GTGACATTCCCGGTATACAGTCAGCGCAGGCCCACCCGGCAGGAGGCAGCGGTTGCACGCGTTTCCGAGCAGGCCCTTGC
CTGCCACGCGCGTGACGGAGCGCCGCTGAAATTGCGCGTAACGGGGCACGAAGAGACAGAGGTGGTGGAACTGCCGGCAG
GCGCAGTTACTCTGCTGATGGAAATTCTCAAGGCCATGGCAGCGGGGCAGGGGGTGACGGTTGTTCCCGATGATGCCGAG
TTGACCACGGTACAGGCTGCAGAGCTTCTGAATGTGTCCCGGCCCTTCCTGATCAAGCTCCTGGAGGAAGGTAAAATTCC
CCATCGCAAGGTCGGGAAGCACCGGCGGGCGCTCATGCAGGACGTGATTGCTTACAAGCGCATCATGGATCGCAGGCGGG
AGGAAATCCTCGACCAACTGGTTGCCGAAGCGCAGGAACAGGGCATGGGATACGGCGCAAGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0U3PC36 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0L0IUA3 |