Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4354169..4354700 Replicon chromosome
Accession NZ_CP013068
Organism Pannonibacter phragmitetus strain 31801

Toxin (Protein)


Gene name stbE Uniprot ID A0A0L0J552
Locus tag APZ00_RS19860 Protein ID WP_050471640.1
Coordinates 4354169..4354465 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0L0J5B6
Locus tag APZ00_RS19865 Protein ID WP_050471641.1
Coordinates 4354455..4354700 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APZ00_RS19830 4350443..4350769 - 327 WP_205630921.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -
APZ00_RS26480 4350766..4353342 - 2577 WP_157757181.1 flagellar hook-length control protein FliK -
APZ00_RS19850 4353478..4353732 + 255 WP_208977399.1 hypothetical protein -
APZ00_RS19855 4353760..4354062 - 303 WP_058899957.1 hypothetical protein -
APZ00_RS19860 4354169..4354465 - 297 WP_050471640.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APZ00_RS19865 4354455..4354700 - 246 WP_050471641.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
APZ00_RS19870 4354840..4356633 - 1794 WP_058899958.1 glucans biosynthesis glucosyltransferase MdoH -
APZ00_RS19875 4356639..4356998 - 360 WP_050471643.1 hypothetical protein -
APZ00_RS19880 4357031..4358605 - 1575 WP_208982589.1 glucan biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-69)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11166.90 Da        Isoelectric Point: 10.5956

>T57862 WP_050471640.1 NZ_CP013068:c4354465-4354169 [Pannonibacter phragmitetus]
MSYELQFLPSALKEWNKLGATIRAQLRKKLAERLQNPRVPGDALHGLQDHYKIKLRSAGYRLVYRVDDLVVTVTVVAVGR
RDSSEVYKDASDRRKGLA

Download         Length: 297 bp

>T57862 NZ_CP013068:c4354465-4354169 [Pannonibacter phragmitetus]
ATGAGCTATGAGCTTCAGTTTCTGCCTTCCGCTTTGAAGGAATGGAACAAACTGGGCGCAACGATCCGGGCTCAGCTGCG
CAAGAAACTGGCCGAGCGCCTGCAGAACCCGCGTGTTCCGGGCGATGCTCTGCATGGCCTGCAGGACCATTACAAGATCA
AGCTCCGCAGCGCAGGCTACCGGCTTGTCTACCGTGTCGACGACCTCGTGGTAACTGTCACTGTGGTGGCCGTTGGCCGC
CGTGACAGCAGTGAAGTCTACAAGGACGCATCAGACAGGCGGAAGGGTCTGGCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8967.38 Da        Isoelectric Point: 4.5960

>AT57862 WP_050471641.1 NZ_CP013068:c4354700-4354455 [Pannonibacter phragmitetus]
MQRIEAKVAVSVSELKKSPSAVLEQAQGETVAVLNHNRIMAYMVPASVFETMIERLDDLELVKVIESRAGETPVRVSLDE
L

Download         Length: 246 bp

>AT57862 NZ_CP013068:c4354700-4354455 [Pannonibacter phragmitetus]
ATGCAGCGTATCGAGGCGAAAGTAGCCGTCAGCGTTTCCGAACTGAAGAAAAGCCCTTCCGCTGTGCTGGAACAGGCGCA
GGGAGAGACGGTTGCTGTGCTCAATCACAACCGCATCATGGCTTACATGGTGCCAGCCAGCGTGTTCGAGACGATGATCG
AGCGCCTGGATGATTTGGAGCTGGTCAAGGTCATCGAGAGCCGTGCCGGTGAGACACCGGTCCGGGTTTCACTTGATGAG
CTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0L0J552

Antitoxin

Source ID Structure
AlphaFold DB A0A0L0J5B6

References