Detailed information of TA system TA057853

Bioinformatically predicted

Overview

TA module

• Type: III
• Classification (family/domain): toxIN/ToxN(toxin)
• Location: 8541..9283
• Replicon: plasmid pYWC2-8-4
• Accession: NZ_CP013059
• Organism: Bacillus thuringiensis strain YWC2-8

Toxin (Protein)

• Gene name: toxN
• Uniprot ID: -
• Locus tag: AQ980_RS31130
• Protein ID: WP_016097319.1
• Coordinates: 8699..9283 (+)
• Length: 195 a.a.

Antitoxin (RNA)

Gene name	toxI
Locus tag	-
Coordinates	8541..8637 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AQ980_RS31110	4091..5722	+	1632	WP_016097315.1	hypothetical protein	-
AQ980_RS31115	5784..6770	+	987	WP_016097316.1	hypothetical protein	-
AQ980_RS31120	6792..7343	+	552	WP_016097317.1	metal-dependent hydrolase	-
AQ980_RS31125	7423..8448	+	1026	WP_016097318.1	DUF3991 and TOPRIM domain-containing protein	-
-	8541..8637	+	97	NuclAT_0	-	Antitoxin
-	8541..8637	+	97	NuclAT_0	-	Antitoxin
-	8541..8637	+	97	NuclAT_0	-	Antitoxin
-	8541..8637	+	97	NuclAT_0	-	Antitoxin
AQ980_RS31130	8699..9283	+	585	WP_016097319.1	type III toxin-antitoxin system ToxN/AbiQ family toxin	Toxin
AQ980_RS31135	9351..10652	+	1302	WP_016097320.1	hypothetical protein	-
AQ980_RS31140	10759..11139	+	381	WP_016097321.1	hypothetical protein	-
AQ980_RS31145	11260..13401	+	2142	WP_016097322.1	type IA DNA topoisomerase	-
AQ980_RS31150	13431..13877	+	447	WP_016097323.1	CPBP family intramembrane metalloprotease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..80699	80699

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ToxN/AbiQ toxin (8-169)

Sequences

Toxin

Protein

• Length: 195 a.a.
• Molecular weight: 22900.17 Da
• Isoelectric Point: 8.9694

>T57853 WP_016097319.1 NZ_CP013059:8699-9283 [Bacillus thuringiensis]
MANKDNPKFYTISTEYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNFNSQVSVKLFDTDEKRIG
VLLVNNMIPVPEKECKEIDIAEKTAADPQYGNLMLKQYLFLKENMDRVTNKVEKVYKDVTVQGKPSHKQKFLKGVCCDFP
KLEEKCQEYKERDQAKERDKARRIAYMRQMGRER

Nucleotide

• Length: 585 bp

>T57853 NZ_CP013059:8699-9283 [Bacillus thuringiensis]
TTGGCTAATAAAGATAATCCTAAATTCTACACCATTTCAACTGAATATATAGATTATTTAAGAGAAACGGATAGTAAAGT
ACCTTTTAATAAAGATGAACAGCATAGTAGACCGTATGTAGGTGTATTGGAAAAAATCAATGGTCATGATTATTTTGTAC
CTTTAACATCACGTAACGATAAAAATTTTAACAGTCAGGTCAGTGTGAAATTATTCGATACTGATGAAAAGCGAATTGGA
GTTTTATTGGTTAATAACATGATTCCAGTCCCAGAAAAAGAGTGTAAAGAAATTGATATAGCAGAAAAAACAGCAGCAGA
CCCTCAGTATGGTAATTTGATGTTAAAACAGTATTTATTTTTAAAAGAAAATATGGATCGAGTTACTAATAAAGTGGAAA
AAGTATATAAAGATGTAACTGTACAAGGAAAGCCTTCACATAAACAAAAATTCTTAAAAGGAGTTTGTTGTGATTTCCCT
AAATTAGAAGAAAAGTGCCAAGAATATAAAGAAAGAGATCAAGCTAAAGAAAGAGATAAAGCTAGAAGAATAGCATATAT
GCGTCAAATGGGGCGTGAGAGATAA

Antitoxin

Nucleotide

• Length: 97 bp

>AT57853 NZ_CP013059:8541-8637 [Bacillus thuringiensis]
GTAACCTTACTTTAGTAGGTGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCGCTAAAAAA

Structures

Antitoxin