Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 4710717..4711310 Replicon chromosome
Accession NZ_CP013046
Organism Serratia marcescens strain B3R3

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag AR325_RS22585 Protein ID WP_076606814.1
Coordinates 4710942..4711310 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag AR325_RS22580 Protein ID WP_139806265.1
Coordinates 4710717..4710878 (+) Length 54 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AR325_RS22565 4709170..4709783 - 614 Protein_4422 transposase -
AR325_RS22570 4709847..4710320 + 474 WP_079007651.1 antirestriction protein -
AR325_RS27165 4710355..4710696 + 342 Protein_4424 hypothetical protein -
AR325_RS22580 4710717..4710878 + 162 WP_139806265.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
AR325_RS22585 4710942..4711310 + 369 WP_076606814.1 TA system toxin CbtA family protein Toxin
AR325_RS22590 4711307..4711635 + 329 Protein_4427 hypothetical protein -
AR325_RS22595 4711733..4712569 + 837 WP_060560317.1 DUF4942 domain-containing protein -
AR325_RS22600 4713465..4713947 + 483 WP_004937362.1 type VI secretion system tube protein Hcp -
AR325_RS22605 4713995..4714477 + 483 WP_004937359.1 type VI secretion system tube protein Hcp -
AR325_RS22610 4714829..4715374 + 546 WP_033632086.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-110)

Antitoxin

Antitoxin CbeA

(1-48)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13660.66 Da        Isoelectric Point: 8.5163

>T57838 WP_076606814.1 NZ_CP013046:4710942-4711310 [Serratia marcescens]
MQTLPVAPKRAAQPCPSPVVVWQSLLTYLLEQHYGLTLNDTEFSDDAVIHKHIDTGISLADAWNFTVEKFDLARTDRRGF
SCLEQSPFITAIDILRARRASGLMTKRGYQAITSVIQGGRRV

Download         Length: 369 bp

>T57838 NZ_CP013046:4710942-4711310 [Serratia marcescens]
ATGCAAACCTTACCGGTCGCCCCGAAACGGGCGGCTCAACCTTGCCCGTCACCTGTTGTTGTCTGGCAATCCTTACTCAC
CTATTTACTGGAACAGCATTACGGTTTGACACTAAACGATACCGAGTTCAGTGATGACGCCGTTATTCATAAACATATTG
ATACCGGCATTTCTCTGGCTGATGCGTGGAATTTCACGGTGGAAAAGTTTGACCTGGCCCGCACCGATCGTCGAGGGTTC
TCCTGCCTGGAACAATCTCCCTTTATCACGGCTATCGATATTCTCCGTGCTCGTCGCGCCTCTGGCCTGATGACAAAGAG
AGGTTACCAAGCCATCACATCAGTTATTCAGGGAGGAAGACGGGTATGA

Antitoxin


Download         Length: 54 a.a.        Molecular weight: 5819.58 Da        Isoelectric Point: 6.1834

>AT57838 WP_139806265.1 NZ_CP013046:4710717-4710878 [Serratia marcescens]
ISNLELMLLSGELNPRHQHCVTLYRNGLTCEADSLGSHGYVYISIYPTPSSPA

Download         Length: 162 bp

>AT57838 NZ_CP013046:4710717-4710878 [Serratia marcescens]
ATCAGCAACCTGGAACTGATGCTGCTTTCTGGTGAACTCAATCCCCGCCATCAGCACTGCGTCACGCTGTATCGCAATGG
ACTGACCTGTGAAGCTGACAGCCTGGGATCACACGGCTATGTGTATATCTCCATTTATCCTACGCCCTCATCACCGGCAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References