Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 3922119..3922666 Replicon chromosome
Accession NZ_CP013021
Organism Agarivorans gilvus strain WH0801

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AR383_RS18670 Protein ID WP_055734499.1
Coordinates 3922119..3922415 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag AR383_RS18675 Protein ID WP_055734500.1
Coordinates 3922424..3922666 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AR383_RS18645 3918269..3918718 + 450 WP_055734494.1 cyanase -
AR383_RS18650 3918775..3919824 - 1050 WP_055734495.1 hemolysin family protein -
AR383_RS18655 3920222..3921190 + 969 WP_055734496.1 hypothetical protein -
AR383_RS18660 3921187..3921561 + 375 WP_055734497.1 hypothetical protein -
AR383_RS18665 3921657..3922034 + 378 WP_055734498.1 hypothetical protein -
AR383_RS18670 3922119..3922415 - 297 WP_055734499.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AR383_RS18675 3922424..3922666 - 243 WP_055734500.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AR383_RS18680 3922967..3923896 - 930 WP_055734501.1 allantoinase PuuE -
AR383_RS18685 3923918..3924649 - 732 WP_055734502.1 aspartate/glutamate racemase family protein -
AR383_RS18690 3924653..3925324 - 672 WP_055734503.1 GntR family transcriptional regulator -
AR383_RS18695 3925597..3927039 + 1443 WP_055734504.1 NCS1 family nucleobase:cation symporter-1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-54)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11357.22 Da        Isoelectric Point: 9.9210

>T57716 WP_055734499.1 NZ_CP013021:c3922415-3922119 [Agarivorans gilvus]
MQKHKYKLSQLAQAHLRKIKGYTISNYSERQWQSYKKTLLTGFQMLADNQALALSCDDIYPNGFYFPLAKHCAYFTKEEG
FILIVAVLGKSQLPQKHL

Download         Length: 297 bp

>T57716 NZ_CP013021:c3922415-3922119 [Agarivorans gilvus]
ATGCAAAAACATAAATACAAACTCAGTCAGCTCGCTCAGGCTCATCTACGCAAAATAAAAGGCTACACCATTAGCAATTA
CTCCGAGCGGCAATGGCAAAGCTACAAAAAGACCCTACTCACTGGATTTCAGATGCTGGCCGACAATCAAGCGCTTGCTT
TAAGTTGTGATGATATTTACCCAAACGGATTTTACTTTCCCCTTGCTAAGCACTGTGCTTATTTTACCAAAGAAGAAGGC
TTCATTTTGATAGTAGCGGTACTGGGAAAATCACAATTACCCCAAAAGCACTTGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8919.13 Da        Isoelectric Point: 4.5858

>AT57716 WP_055734500.1 NZ_CP013021:c3922666-3922424 [Agarivorans gilvus]
MQTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDFEELEAMKADYLKHCFEAAKQDLAQGNVVDGEDFINSL

Download         Length: 243 bp

>AT57716 NZ_CP013021:c3922666-3922424 [Agarivorans gilvus]
ATGCAAACATTAACAGCAAATGATGCGAAACGTAATTTTGGTGAATTGCTGCTTAGCGCCCAACGAGAGCCGGTAAAGAT
TAGTAAGAACAGTAAAGACGCGGTAGTCGTTATGTCTATCAAAGATTTTGAAGAGCTAGAAGCGATGAAAGCGGATTACC
TTAAACACTGCTTCGAGGCCGCCAAGCAAGACTTAGCGCAAGGCAATGTGGTTGATGGTGAAGACTTCATAAATTCCTTA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References