Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 3752377..3752936 Replicon chromosome
Accession NZ_CP013021
Organism Agarivorans gilvus strain WH0801

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AR383_RS17800 Protein ID WP_055734349.1
Coordinates 3752377..3752655 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AR383_RS17805 Protein ID WP_055734350.1
Coordinates 3752652..3752936 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AR383_RS17780 3747653..3748918 - 1266 WP_055734345.1 HAMP domain-containing histidine kinase -
AR383_RS17785 3748918..3749592 - 675 WP_055734346.1 response regulator transcription factor -
AR383_RS17790 3749743..3750117 - 375 WP_055734347.1 diacylglycerol kinase -
AR383_RS17795 3750140..3751732 - 1593 WP_055734348.1 phosphoethanolamine--lipid A transferase -
AR383_RS17800 3752377..3752655 - 279 WP_055734349.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
AR383_RS17805 3752652..3752936 - 285 WP_055734350.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AR383_RS17810 3753264..3754028 + 765 WP_055734351.1 hypothetical protein -
AR383_RS17815 3754506..3755243 - 738 WP_055734352.1 NYN domain-containing protein -
AR383_RS17820 3755471..3756214 - 744 WP_055734353.1 metallophosphatase family protein -
AR383_RS17825 3756318..3756682 - 365 Protein_3476 cupin domain-containing protein -
AR383_RS17830 3756685..3757512 - 828 WP_055734354.1 PhzF family phenazine biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10822.47 Da        Isoelectric Point: 4.3430

>T57715 WP_055734349.1 NZ_CP013021:c3752655-3752377 [Agarivorans gilvus]
MILWEEESINDREKIFEFLYDFNPDAAEKTDDIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSAIRVM
RVLHQKQKFPTE

Download         Length: 279 bp

>T57715 NZ_CP013021:c3752655-3752377 [Agarivorans gilvus]
ATGATTTTATGGGAAGAAGAATCGATAAATGATCGTGAGAAGATCTTCGAGTTTCTTTATGACTTCAACCCTGACGCGGC
AGAAAAAACTGACGATATTATTGAAGCTAAAGTAGAAAATTTACTTGAACAACCACTGATGGGTGTTCAACGTGATGGCA
TTCGAGGGCGATTACTCATTATCCCCGAAATCTCAATGATCGTTTCCTACTGGGTTGACGGCTCAGCAATTCGTGTAATG
CGAGTTCTACACCAGAAGCAGAAATTCCCTACCGAATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10805.11 Da        Isoelectric Point: 8.0515

>AT57715 WP_055734350.1 NZ_CP013021:c3752936-3752652 [Agarivorans gilvus]
MDTRIQFRVDDEVKRLAQQLAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKLDSGKASFIDHDSAKAR
MAERKAKIRSRGQQ

Download         Length: 285 bp

>AT57715 NZ_CP013021:c3752936-3752652 [Agarivorans gilvus]
ATGGACACTAGAATTCAATTTCGTGTTGATGACGAAGTTAAGCGCTTAGCTCAGCAACTAGCAGAGAGCCAAGGTCGCAC
ACTTAGCGATGCTTGCCGTGAGCTTACCGAGCAAATGGCTGAGCAACAACGAAAAGCATTATCTCATGACGCTTGGTTAA
CTGAACAAGTAAACCTAGCATTTGAAAAGCTTGACTCAGGAAAAGCTTCATTTATTGATCATGACTCAGCAAAGGCACGA
ATGGCTGAACGAAAGGCCAAGATTCGTAGCCGAGGTCAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References