57691

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 443799..444160 Replicon chromosome
Accession NZ_CP013006
Organism Xanthomonas citri pv. malvacearum strain XcmN1003

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag APY30_RS01970 Protein ID WP_005914328.1
Coordinates 444026..444160 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag APY30_RS01965 Protein ID WP_003486606.1
Coordinates 443799..443951 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APY30_RS01930 438855..439538 - 684 WP_003486617.1 dTMP kinase -
APY30_RS01940 440020..440562 - 543 WP_003486615.1 GTPase -
APY30_RS01945 440559..441476 - 918 WP_033481739.1 hypothetical protein -
APY30_RS01950 441573..441932 - 360 WP_003486613.1 hypothetical protein -
APY30_RS01955 441996..442448 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
APY30_RS01960 442769..443692 + 924 WP_005914327.1 arginase -
APY30_RS01965 443799..443951 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
APY30_RS01970 444026..444160 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
APY30_RS01975 444387..444596 + 210 WP_003486601.1 CsbD family protein -
APY30_RS01980 444778..446067 + 1290 WP_005914329.1 tryptophan--tRNA ligase -
APY30_RS01985 446106..447140 + 1035 WP_050554793.1 MBL fold metallo-hydrolase -
APY30_RS01990 447332..449023 + 1692 WP_033479687.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T57691 WP_005914328.1 NZ_CP013006:444026-444160 [Xanthomonas citri pv. malvacearum]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T57691 NZ_CP013006:444026-444160 [Xanthomonas citri pv. malvacearum]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTATCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT57691 WP_003486606.1 NZ_CP013006:443799-443951 [Xanthomonas citri pv. malvacearum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT57691 NZ_CP013006:443799-443951 [Xanthomonas citri pv. malvacearum]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References