Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 222461..222998 Replicon chromosome
Accession NZ_CP013004
Organism Xanthomonas citri pv. malvacearum strain XcmH1005

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag APY29_RS00990 Protein ID WP_017158383.1
Coordinates 222461..222742 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag APY29_RS00995 Protein ID WP_017158384.1
Coordinates 222729..222998 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APY29_RS00965 218268..219841 - 1574 Protein_183 type IV secretion system DNA-binding domain-containing protein -
APY29_RS24830 219845..220018 - 174 WP_164722239.1 hypothetical protein -
APY29_RS00970 220018..220413 - 396 WP_039447651.1 hypothetical protein -
APY29_RS00975 220772..221218 + 447 WP_017160486.1 hypothetical protein -
APY29_RS00980 221227..221922 + 696 WP_017154898.1 hypothetical protein -
APY29_RS00985 221970..222323 + 354 WP_017160495.1 hypothetical protein -
APY29_RS00990 222461..222742 - 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
APY29_RS00995 222729..222998 - 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
APY29_RS01000 223107..223553 - 447 WP_089504520.1 resolvase -
APY29_RS01005 224267..225412 - 1146 WP_025990656.1 DUF4236 domain-containing protein -
APY29_RS01010 225810..226181 - 372 Protein_193 recombinase family protein -
APY29_RS01020 226733..227014 - 282 WP_017161425.1 hypothetical protein -
APY29_RS01025 227038..227736 - 699 WP_078538983.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 202575..225753 23178


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T57686 WP_017158383.1 NZ_CP013004:c222742-222461 [Xanthomonas citri pv. malvacearum]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T57686 NZ_CP013004:c222742-222461 [Xanthomonas citri pv. malvacearum]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCCGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT57686 WP_017158384.1 NZ_CP013004:c222998-222729 [Xanthomonas citri pv. malvacearum]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT57686 NZ_CP013004:c222998-222729 [Xanthomonas citri pv. malvacearum]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06

Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References