Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3221354..3221805 Replicon chromosome
Accession NZ_CP013002
Organism Caulobacter henricii strain CB4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AQ619_RS18885 Protein ID WP_084746078.1
Coordinates 3221530..3221805 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AQ619_RS18880 Protein ID WP_084746075.1
Coordinates 3221354..3221530 (+) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AQ619_RS15020 3216538..3217101 - 564 WP_062149395.1 peptidoglycan-associated lipoprotein Pal -
AQ619_RS15025 3217272..3218567 - 1296 WP_062149398.1 Tol-Pal system protein TolB -
AQ619_RS15030 3218588..3219358 - 771 WP_062151739.1 energy transducer TonB -
AQ619_RS15035 3219366..3219914 - 549 WP_062149401.1 biopolymer transporter ExbD -
AQ619_RS15040 3219918..3220619 - 702 WP_062149403.1 protein TolQ -
AQ619_RS15045 3220735..3221193 - 459 WP_062149406.1 YbgC/FadM family acyl-CoA thioesterase -
AQ619_RS18880 3221354..3221530 + 177 WP_084746075.1 CopG family transcriptional regulator Antitoxin
AQ619_RS18885 3221530..3221805 + 276 WP_084746078.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AQ619_RS15050 3221821..3222672 - 852 WP_062149409.1 hypothetical protein -
AQ619_RS15055 3222676..3223716 - 1041 WP_062149412.1 Holliday junction branch migration DNA helicase RuvB -
AQ619_RS15060 3223745..3224362 - 618 WP_062149415.1 Holliday junction branch migration protein RuvA -
AQ619_RS15065 3224376..3224897 - 522 WP_174515191.1 crossover junction endodeoxyribonuclease RuvC -
AQ619_RS15070 3225018..3226442 + 1425 WP_062149421.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10313.77 Da        Isoelectric Point: 10.9425

>T57683 WP_084746078.1 NZ_CP013002:3221530-3221805 [Caulobacter henricii]
VRRIVWTVEAVSNLESIFAYVSAFNASAAVRLARRLQSAADSLATHPDRGRETRSGLRELTIIHPYLIRYRVRDDAILIL
RIRHGAQDAET

Download         Length: 276 bp

>T57683 NZ_CP013002:3221530-3221805 [Caulobacter henricii]
GTGCGGCGGATTGTCTGGACGGTGGAAGCCGTGTCCAACCTCGAAAGCATTTTCGCATACGTGTCAGCGTTCAACGCATC
TGCGGCTGTTCGTCTGGCGCGACGCCTGCAATCGGCGGCTGACAGCTTGGCGACCCATCCCGATCGTGGGCGGGAAACGC
GCTCTGGACTGCGAGAACTCACGATCATCCATCCCTACCTCATCCGCTACCGGGTCAGGGACGACGCGATTCTGATCCTG
CGAATTCGTCACGGCGCGCAAGACGCTGAGACCTGA

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6080.65 Da        Isoelectric Point: 4.1630

>AT57683 WP_084746075.1 NZ_CP013002:3221354-3221530 [Caulobacter henricii]
MKIEPAIFDETDDAAEVAADARAEADVAAGRLVSHEAVSRWLKSWSDGAPTPAPKSGD

Download         Length: 177 bp

>AT57683 NZ_CP013002:3221354-3221530 [Caulobacter henricii]
ATGAAGATCGAACCCGCCATCTTCGATGAAACAGACGATGCCGCAGAAGTCGCCGCCGACGCGCGCGCCGAAGCCGACGT
CGCCGCGGGTCGCCTTGTCAGCCATGAAGCGGTGAGCCGCTGGCTGAAGTCGTGGTCCGATGGCGCACCTACGCCCGCGC
CTAAATCTGGCGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References