Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4685044..4685189 Replicon chromosome
Accession NZ_CP012987
Organism Klebsiella pneumoniae strain KpN01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4685080..4685182 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4685044..4685189 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AQD68_RS23360 4680174..4682234 + 2061 WP_004151449.1 oligopeptidase B -
AQD68_RS23365 4682238..4682897 - 660 WP_021440386.1 exodeoxyribonuclease X -
AQD68_RS23370 4682976..4683206 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AQD68_RS23375 4683319..4683693 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AQD68_RS23380 4683697..4684566 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AQD68_RS23385 4684583..4684921 + 339 WP_002911404.1 YebY family protein -
- 4685044..4685189 - 146 - - Antitoxin
- 4685080..4685182 + 103 - - Toxin
AQD68_RS31930 4685557..4685700 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AQD68_RS23395 4685805..4686773 - 969 WP_073971755.1 VirK/YbjX family protein -
AQD68_RS23400 4686930..4687583 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
AQD68_RS23405 4687580..4687771 - 192 WP_002911395.1 YebW family protein -
AQD68_RS23410 4687869..4688108 - 240 WP_002911393.1 YebV family protein -
AQD68_RS23415 4688224..4689657 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T57616 NZ_CP012987:4685080-4685182 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT57616 NZ_CP012987:c4685189-4685044 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References