Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 467936..468537 Replicon chromosome
Accession NZ_CP012969
Organism Psychrobacter sp. AntiMn-1

Toxin (Protein)


Gene name relB Uniprot ID X0QP36
Locus tag AOT82_RS01865 Protein ID WP_037025847.1
Coordinates 467936..468196 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1D9CW61
Locus tag AOT82_RS01870 Protein ID WP_071001554.1
Coordinates 468232..468537 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOT82_RS01855 464702..466480 - 1779 WP_197496767.1 ABC transporter ATP-binding protein/permease -
AOT82_RS01860 466594..467838 - 1245 WP_156771002.1 2-methylaconitate cis-trans isomerase PrpF -
AOT82_RS01865 467936..468196 - 261 WP_037025847.1 Txe/YoeB family addiction module toxin Toxin
AOT82_RS01870 468232..468537 - 306 WP_071001554.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AOT82_RS01875 468766..471399 - 2634 WP_071003606.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
AOT82_RS01880 471501..472325 - 825 WP_071001555.1 toll/interleukin-1 receptor domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10333.75 Da        Isoelectric Point: 8.4514

>T57518 WP_037025847.1 NZ_CP012969:c468196-467936 [Psychrobacter sp. AntiMn-1]
MSEQLAWTDAAWKDYLYWQTQDKKTLKRINKLITECKRNPFEGIGKPEPLKENLSGFWSRRIDDANRLVYAVDDNYLTII
SCRYHY

Download         Length: 261 bp

>T57518 NZ_CP012969:c468196-467936 [Psychrobacter sp. AntiMn-1]
ATGAGTGAGCAACTAGCTTGGACAGATGCTGCGTGGAAGGACTATCTGTACTGGCAAACGCAAGACAAAAAAACACTCAA
ACGTATTAACAAACTCATCACCGAATGTAAGCGTAATCCGTTTGAAGGTATTGGCAAACCTGAACCCCTAAAAGAGAACC
TATCCGGATTTTGGTCAAGACGCATCGATGATGCCAATCGGTTGGTATATGCCGTCGATGACAATTATCTGACGATTATC
TCTTGTCGCTATCATTATTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11136.23 Da        Isoelectric Point: 4.3175

>AT57518 WP_071001554.1 NZ_CP012969:c468537-468232 [Psychrobacter sp. AntiMn-1]
MRVVSFSEARKHLKSVLDTVNDDANATIVTRRDADDAVVMSLDYYNSLMETVYLLKSPANAAHLAESIAQYKAGKTVTRD
LIDTAESSDDNEHTDSDIENA

Download         Length: 306 bp

>AT57518 NZ_CP012969:c468537-468232 [Psychrobacter sp. AntiMn-1]
ATGAGAGTCGTTAGTTTTTCAGAAGCAAGAAAGCACCTAAAATCTGTCCTAGACACGGTAAACGATGATGCCAACGCTAC
TATCGTAACTCGCCGTGACGCTGATGATGCGGTTGTGATGTCGCTTGATTATTACAATAGCCTGATGGAAACCGTCTATT
TGCTCAAATCTCCTGCCAATGCGGCGCACTTAGCGGAATCTATTGCCCAATATAAAGCTGGCAAGACTGTCACGCGTGAC
CTAATTGATACAGCAGAAAGCAGCGATGACAATGAGCATACGGATAGCGATATTGAAAATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB X0QP36

Antitoxin

Source ID Structure
AlphaFold DB A0A1D9CW61

References