Detailed information of TA system TA057483

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2720116..2720672
• Replicon: chromosome
• Accession: NZ_CP012947
• Organism: Xanthomonas oryzae pv. oryzae strain PXO83

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: APZ20_RS12845
• Protein ID: WP_027703932.1
• Coordinates: 2720116..2720406 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: APZ20_RS12850
• Protein ID: WP_011408759.1
• Coordinates: 2720394..2720672 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APZ20_RS12810	2715462..2715778	-	317	Protein_2418	ATP-dependent DNA ligase	-
APZ20_RS27945	2715838..2716044	-	207	Protein_2419	hypothetical protein	-
APZ20_RS25035	2716060..2716236	-	177	Protein_2420	DUF3606 domain-containing protein	-
APZ20_RS12820	2716458..2716859	+	402	WP_011259345.1	H-NS histone family protein	-
APZ20_RS12830	2717283..2718757	-	1475	Protein_2422	IS5 family transposase	-
APZ20_RS12835	2719335..2719514	-	180	WP_015463309.1	hypothetical protein	-
APZ20_RS25040	2719785..2720039	-	255	WP_198912806.1	hypothetical protein	-
APZ20_RS12845	2720116..2720406	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
APZ20_RS12850	2720394..2720672	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
APZ20_RS28140	2720753..2720956	-	204	WP_198912807.1	hypothetical protein	-
APZ20_RS28145	2720868..2721212	-	345	WP_198912817.1	hypothetical protein	-
APZ20_RS25050	2721157..2721357	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
APZ20_RS12855	2721606..2722562	-	957	WP_041182719.1	IS30-like element IS1112b family transposase	-
APZ20_RS12860	2722964..2723932	-	969	WP_012445118.1	IS5-like element ISXo1 family transposase	-
APZ20_RS12865	2724336..2725520	-	1185	WP_011408397.1	IS256 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	2717585..2727066	9481

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T57483 WP_027703932.1 NZ_CP012947:c2720406-2720116 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T57483 NZ_CP012947:c2720406-2720116 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT57483 WP_011408759.1 NZ_CP012947:c2720672-2720394 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT57483 NZ_CP012947:c2720672-2720394 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2