Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 1347455..1347983 Replicon chromosome
Accession NZ_CP012946
Organism Blastochloris viridis strain ATCC 19567

Toxin (Protein)


Gene name stbE Uniprot ID A0A0H5BJ02
Locus tag BVIR_RS05925 Protein ID WP_055036861.1
Coordinates 1347693..1347983 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0H5BFZ2
Locus tag BVIR_RS05920 Protein ID WP_055036860.1
Coordinates 1347455..1347703 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVIR_RS05890 1342475..1344727 - 2253 WP_055036854.1 phage tail length tape measure family protein -
BVIR_RS05895 1344732..1344956 - 225 WP_055036855.1 hypothetical protein -
BVIR_RS05900 1344953..1345393 - 441 WP_055036856.1 hypothetical protein -
BVIR_RS17105 1346644..1346919 - 276 Protein_1182 hypothetical protein -
BVIR_RS05915 1346936..1347370 - 435 WP_055036859.1 hypothetical protein -
BVIR_RS05920 1347455..1347703 + 249 WP_055036860.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BVIR_RS05925 1347693..1347983 + 291 WP_055036861.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BVIR_RS05930 1347991..1348620 - 630 WP_055036862.1 hypothetical protein -
BVIR_RS05935 1348622..1348936 - 315 WP_055036863.1 hypothetical protein -
BVIR_RS05940 1348933..1349271 - 339 WP_055036864.1 DUF2190 family protein -
BVIR_RS05945 1349356..1351314 - 1959 WP_055036865.1 HK97 family phage prohead protease -
BVIR_RS05950 1351332..1352858 - 1527 WP_055036866.1 phage portal protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1325747..1390708 64961


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11310.14 Da        Isoelectric Point: 10.3633

>T57480 WP_055036861.1 NZ_CP012946:1347693-1347983 [Blastochloris viridis]
MSYELAFLDEALKEWRKLDSTMRDQFKAKLAERLENPNIPSARLHGAKERYKIKLRSAGYRLVYEVRDLELLVLVVAVGK
RERNEIYKTAARRKAD

Download         Length: 291 bp

>T57480 NZ_CP012946:1347693-1347983 [Blastochloris viridis]
ATGAGCTATGAGCTCGCCTTCCTCGACGAGGCGTTGAAGGAATGGCGCAAGCTCGACAGCACCATGCGAGACCAGTTCAA
GGCCAAGCTCGCCGAGAGATTGGAAAACCCGAATATTCCCTCCGCGCGTCTCCATGGCGCAAAGGAACGCTACAAGATTA
AGCTGCGCAGCGCCGGTTATCGGCTGGTCTATGAGGTTCGGGACCTGGAGCTGCTGGTTCTCGTTGTCGCCGTCGGCAAG
CGGGAACGCAACGAAATCTACAAGACGGCAGCCCGGCGGAAAGCGGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8860.09 Da        Isoelectric Point: 4.5778

>AT57480 WP_055036860.1 NZ_CP012946:1347455-1347703 [Blastochloris viridis]
MAHAVHATTVASISDLKKNPMGTVAAGEGFPVAILNRNEPAFYCIPAKAYEELLERLEDLELNAIADAREGQAIHKVSLD
EL

Download         Length: 249 bp

>AT57480 NZ_CP012946:1347455-1347703 [Blastochloris viridis]
ATGGCGCATGCCGTTCACGCCACTACGGTCGCCAGCATTTCGGACCTGAAGAAAAATCCCATGGGCACGGTCGCTGCCGG
CGAAGGCTTCCCCGTCGCGATCCTCAACCGCAACGAACCGGCCTTCTATTGCATCCCGGCCAAGGCTTACGAGGAACTGC
TGGAGCGGCTCGAAGACCTTGAGTTGAACGCCATCGCGGACGCTCGCGAGGGTCAGGCGATCCACAAGGTTTCGCTCGAT
GAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H5BJ02

Antitoxin

Source ID Structure
AlphaFold DB A0A0H5BFZ2

References