57441

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3678257..3678599 Replicon chromosome
Accession NZ_CP012900
Organism Stenotrophomonas acidaminiphila strain ZAC14D2_NAIMI4_2

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0S1B3P0
Locus tag AOT14_RS16330 Protein ID WP_054667984.1
Coordinates 3678257..3678391 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0S1B3Z5
Locus tag AOT14_RS16335 Protein ID WP_054667986.1
Coordinates 3678447..3678599 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOT14_RS16305 3674069..3675067 - 999 WP_054667977.1 MBL fold metallo-hydrolase -
AOT14_RS16310 3675193..3675492 - 300 WP_054668805.1 hypothetical protein -
AOT14_RS16315 3675571..3676863 - 1293 WP_054667980.1 tryptophan--tRNA ligase -
AOT14_RS16320 3676973..3677764 + 792 WP_054667981.1 hypothetical protein -
AOT14_RS16325 3677835..3678056 - 222 WP_054667983.1 CsbD family protein -
AOT14_RS16330 3678257..3678391 - 135 WP_054667984.1 entericidin A/B family lipoprotein Toxin
AOT14_RS16335 3678447..3678599 - 153 WP_054667986.1 entericidin A/B family lipoprotein Antitoxin
AOT14_RS16340 3678727..3679647 - 921 WP_054667987.1 arginase -
AOT14_RS16345 3679857..3681254 + 1398 WP_054667990.1 oxygen-independent coproporphyrinogen III oxidase -
AOT14_RS16350 3681274..3682029 + 756 WP_054667992.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4626.55 Da        Isoelectric Point: 10.2040

>T57441 WP_054667984.1 NZ_CP012900:c3678391-3678257 [Stenotrophomonas acidaminiphila]
MKRMVALMMLSLFSIAVLSGCNTVAGAGKDVQKAGEKVEDAAKR

Download         Length: 135 bp

>T57441 NZ_CP012900:c3678391-3678257 [Stenotrophomonas acidaminiphila]
ATGAAGCGCATGGTTGCCCTGATGATGCTGTCGTTGTTCTCGATCGCGGTGCTGTCCGGCTGCAATACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCCGGCGAGAAGGTGGAGGACGCAGCCAAGCGCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5203.10 Da        Isoelectric Point: 7.7213

>AT57441 WP_054667986.1 NZ_CP012900:c3678599-3678447 [Stenotrophomonas acidaminiphila]
MKRVLMLALLAMFSAGTLSACNTVAGAGKDMQKAGEKVEDKAHDCSDGKC

Download         Length: 153 bp

>AT57441 NZ_CP012900:c3678599-3678447 [Stenotrophomonas acidaminiphila]
ATGAAGCGAGTACTGATGCTGGCCCTGCTGGCCATGTTTTCGGCGGGAACGCTCAGCGCCTGCAACACCGTCGCCGGCGC
CGGCAAGGACATGCAGAAGGCCGGTGAGAAGGTCGAGGACAAGGCCCACGACTGCAGCGACGGCAAGTGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0S1B3P0

Antitoxin

Source ID Structure
AlphaFold DB A0A0S1B3Z5

References