Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 712655..712800 Replicon chromosome
Accession NZ_CP012883
Organism Klebsiella pneumoniae KP-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 712662..712764 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 712655..712800 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KLP1_RS03585 708186..709619 + 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KLP1_RS03590 709735..709974 + 240 WP_002911393.1 YebV family protein -
KLP1_RS03595 710072..710263 + 192 WP_002911395.1 YebW family protein -
KLP1_RS03600 710260..710913 - 654 WP_021440384.1 protein-serine/threonine phosphatase -
KLP1_RS03605 711070..712038 + 969 WP_014907334.1 VirK/YbjX family protein -
KLP1_RS28585 712143..712286 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 712655..712800 + 146 - - Antitoxin
- 712662..712764 - 103 - - Toxin
KLP1_RS03615 712923..713261 - 339 WP_002911404.1 YebY family protein -
KLP1_RS03620 713278..714147 - 870 WP_021440385.1 copper homeostasis membrane protein CopD -
KLP1_RS03625 714151..714525 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KLP1_RS03630 714638..714868 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KLP1_RS03635 714947..715606 + 660 WP_021440386.1 exodeoxyribonuclease X -
KLP1_RS03640 715610..717670 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T57407 NZ_CP012883:c712764-712662 [Klebsiella pneumoniae KP-1]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT57407 NZ_CP012883:712655-712800 [Klebsiella pneumoniae KP-1]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References