Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2718335..2718606 Replicon chromosome
Accession NZ_CP012870
Organism Escherichia coli strain K-12 substr. MG1655_TMP32XR2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2718465..2718568 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2718335..2718606 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR63_RS13270 2714890..2715552 - 663 WP_000944256.1 exodeoxyribonuclease X -
QR63_RS13275 2715576..2716232 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
QR63_RS13280 2716334..2716564 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QR63_RS13285 2716703..2717077 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QR63_RS13290 2717081..2717953 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
QR63_RS13295 2717966..2718307 + 342 WP_000976476.1 YebY family protein -
- 2718335..2718606 - 272 - - Antitoxin
- 2718465..2718568 + 104 - - Toxin
QR63_RS13305 2718703..2719359 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QR63_RS13310 2719360..2719551 - 192 WP_000457842.1 YebW family protein -
QR63_RS13315 2719656..2719892 - 237 WP_001295499.1 DUF1480 family protein -
QR63_RS13320 2720010..2721449 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T57362 NZ_CP012870:2718465-2718568 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT57362 NZ_CP012870:c2718606-2718335 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References