Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2718328..2718599 Replicon chromosome
Accession NZ_CP012868
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2718458..2718561 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2718328..2718599 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ24_RS13265 2714883..2715545 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQ24_RS13270 2715569..2716225 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
QQ24_RS13275 2716327..2716557 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQ24_RS13280 2716696..2717070 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQ24_RS13285 2717074..2717946 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
QQ24_RS13290 2717959..2718300 + 342 WP_000976476.1 YebY family protein -
- 2718328..2718599 - 272 - - Antitoxin
- 2718458..2718561 + 104 - - Toxin
QQ24_RS13300 2718696..2719352 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QQ24_RS13305 2719353..2719544 - 192 WP_000457842.1 YebW family protein -
QQ24_RS13310 2719649..2719885 - 237 WP_001295499.1 DUF1480 family protein -
QQ24_RS13315 2720003..2721442 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T57300 NZ_CP012868:2718458-2718561 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT57300 NZ_CP012868:c2718599-2718328 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References