Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1659142..1659784 Replicon chromosome
Accession NZ_CP012832
Organism Synechocystis sp. PCC 6803 substr. GT-G

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AOY38_RS07810 Protein ID WP_010872706.1
Coordinates 1659350..1659784 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AOY38_RS07805 Protein ID WP_010872705.1
Coordinates 1659142..1659360 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY38_RS07790 1654362..1654745 - 384 WP_010872702.1 heterocyst frequency control protein PatD -
AOY38_RS07795 1655116..1657398 + 2283 WP_010872703.1 RelA/SpoT family protein -
AOY38_RS07800 1657584..1658861 - 1278 WP_010872704.1 adenosylhomocysteinase -
AOY38_RS07805 1659142..1659360 + 219 WP_010872705.1 hypothetical protein Antitoxin
AOY38_RS07810 1659350..1659784 + 435 WP_010872706.1 putative toxin-antitoxin system toxin component, PIN family Toxin
AOY38_RS07815 1659812..1660696 - 885 WP_010872707.1 transglutaminase family protein -
AOY38_RS07820 1660795..1661358 - 564 WP_010872708.1 Uma2 family endonuclease -
AOY38_RS07825 1661379..1662578 - 1200 WP_010872709.1 glycosyltransferase family 4 protein -
AOY38_RS07830 1662627..1663763 - 1137 WP_010872710.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16459.94 Da        Isoelectric Point: 4.4099

>T57268 WP_010872706.1 NZ_CP012832:1659350-1659784 [Synechocystis sp. PCC 6803]
MNNEVIRVVIDTNIWISFLIGKTLQGLNQAIIDNQVVILFSDTLFTELMEVLHHPKFKKYFSGTAIQNLIALLNEKVELV
EVNLHFDSYRDKKDNFLLDLAVSGNANYLVTGDSDLLTLNPFDNVEIISYQHFQAIILAMMDNQ

Download         Length: 435 bp

>T57268 NZ_CP012832:1659350-1659784 [Synechocystis sp. PCC 6803]
ATGAACAATGAAGTTATCCGGGTTGTAATTGATACGAATATCTGGATCAGTTTTCTAATTGGAAAAACTCTTCAAGGTTT
AAATCAAGCCATCATTGATAACCAAGTGGTCATTTTATTCAGTGACACTTTGTTTACTGAGCTGATGGAAGTATTACACC
ATCCTAAATTCAAAAAGTACTTTTCCGGAACAGCCATCCAAAATTTAATCGCACTGTTAAACGAAAAAGTTGAATTGGTT
GAAGTGAATCTTCATTTTGACAGTTATCGAGACAAAAAAGATAATTTCTTGCTGGATTTGGCAGTCTCAGGCAATGCAAA
TTATTTGGTGACGGGAGATAGTGACCTATTGACATTAAACCCATTTGACAATGTAGAAATTATCTCCTATCAACATTTTC
AAGCTATTATTTTAGCCATGATGGATAATCAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8400.43 Da        Isoelectric Point: 4.2583

>AT57268 WP_010872705.1 NZ_CP012832:1659142-1659360 [Synechocystis sp. PCC 6803]
MHSLSSLEFPELKSVIAQCNLEEKLELLELLEKDTFGTRFNKFLNSVKTDELTLEDITQEVESVRQANYHEQ

Download         Length: 219 bp

>AT57268 NZ_CP012832:1659142-1659360 [Synechocystis sp. PCC 6803]
ATGCACTCATTGTCATCACTGGAATTTCCTGAGCTTAAAAGTGTTATTGCCCAATGTAATCTTGAAGAAAAACTTGAATT
ATTAGAACTTTTGGAAAAGGATACTTTTGGCACCAGATTTAACAAATTTTTAAATTCTGTCAAAACTGACGAATTAACCT
TAGAAGACATTACACAAGAAGTTGAATCGGTCCGGCAAGCTAATTATCATGAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References