57265

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4924148..4924695 Replicon chromosome
Accession NZ_CP012831
Organism Pseudomonas fluorescens strain FW300-N2C3

Toxin (Protein)


Gene name relE Uniprot ID A0A0N9X2E3
Locus tag AO356_RS22025 Protein ID WP_060741540.1
Coordinates 4924148..4924423 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1I5FZB6
Locus tag AO356_RS22030 Protein ID WP_060741541.1
Coordinates 4924423..4924695 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AO356_RS22005 4919569..4921407 + 1839 WP_024617381.1 amidohydrolase -
AO356_RS22010 4921562..4922191 + 630 WP_014337664.1 hydrolase -
AO356_RS22015 4922437..4923315 + 879 WP_060741538.1 LysR family transcriptional regulator -
AO356_RS22020 4923368..4923844 - 477 WP_060741539.1 hemerythrin domain-containing protein -
AO356_RS22025 4924148..4924423 - 276 WP_060741540.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AO356_RS22030 4924423..4924695 - 273 WP_060741541.1 ribbon-helix-helix domain-containing protein Antitoxin
AO356_RS22035 4924957..4926420 - 1464 WP_060741542.1 NADH-quinone oxidoreductase subunit NuoN -
AO356_RS22040 4926428..4927960 - 1533 WP_060741543.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10692.24 Da        Isoelectric Point: 8.5042

>T57265 WP_060741540.1 NZ_CP012831:c4924423-4924148 [Pseudomonas fluorescens]
MELKWTSKALSDIARLYEFLASANQPAAARTVQQLTTAPTSLLVNPRMGERLEEFEPRDVRRIQVGHYEMRYEIVGSTLY
LLRLWHTREDR

Download         Length: 276 bp

>T57265 NZ_CP012831:c4924423-4924148 [Pseudomonas fluorescens]
ATGGAGTTGAAGTGGACCAGCAAGGCACTGTCCGACATAGCCCGACTCTATGAGTTTCTGGCATCGGCGAACCAACCCGC
TGCCGCACGAACAGTACAACAGCTCACGACTGCACCGACCTCATTGCTGGTCAACCCGCGCATGGGTGAACGCCTGGAAG
AGTTCGAACCTCGGGATGTGCGCAGAATTCAGGTCGGCCACTACGAGATGCGCTACGAAATAGTAGGTTCCACCCTGTAC
CTGCTGCGCCTGTGGCACACACGTGAGGATCGATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10118.44 Da        Isoelectric Point: 5.1007

>AT57265 WP_060741541.1 NZ_CP012831:c4924695-4924423 [Pseudomonas fluorescens]
MATTTKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTLEALADVDAGRVIDHQAVQAWADSL
NTDTPLPVPR

Download         Length: 273 bp

>AT57265 NZ_CP012831:c4924695-4924423 [Pseudomonas fluorescens]
ATGGCAACCACCACGAAAACTCGCTCTGTCACCGCCCACGTCCCAGTGCAACTGGCCGAAAAAGTCGACCTGATGGCTGA
ACGCCTTGAGCGCTCCAGGAACTGGATCGTCAAACAGGCTCTATCTGCTTGGATAGATCAGGAAGAGGAGCGCAGTCGTC
TGACCCTCGAGGCCCTGGCCGATGTTGACGCTGGCCGTGTGATTGATCACCAGGCGGTCCAGGCTTGGGCCGATAGTCTC
AATACCGACACTCCGTTACCGGTCCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N9X2E3

Antitoxin

Source ID Structure
AlphaFold DB A0A1I5FZB6

References