Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-StbC |
| Location | 2768209..2768869 | Replicon | chromosome |
| Accession | NZ_CP012746 | ||
| Organism | Paraburkholderia caribensis MBA4 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | K788_RS12305 | Protein ID | WP_082624873.1 |
| Coordinates | 2768209..2768637 (-) | Length | 143 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | K788_RS12310 | Protein ID | WP_035991398.1 |
| Coordinates | 2768624..2768869 (-) | Length | 82 a.a. |
Genomic Context
Location: 2765772..2766410 (639 bp)
Type: Others
Protein ID: WP_035991009.1
Type: Others
Protein ID: WP_035991009.1
Location: 2769038..2769658 (621 bp)
Type: Others
Protein ID: WP_035991001.1
Type: Others
Protein ID: WP_035991001.1
Location: 2772758..2773270 (513 bp)
Type: Others
Protein ID: WP_035990992.1
Type: Others
Protein ID: WP_035990992.1
Location: 2764260..2765216 (957 bp)
Type: Others
Protein ID: WP_035991011.1
Type: Others
Protein ID: WP_035991011.1
Location: 2766453..2767430 (978 bp)
Type: Others
Protein ID: WP_035991007.1
Type: Others
Protein ID: WP_035991007.1
Location: 2767635..2768108 (474 bp)
Type: Others
Protein ID: WP_082624872.1
Type: Others
Protein ID: WP_082624872.1
Location: 2768209..2768637 (429 bp)
Type: Toxin
Protein ID: WP_082624873.1
Type: Toxin
Protein ID: WP_082624873.1
Location: 2768624..2768869 (246 bp)
Type: Antitoxin
Protein ID: WP_035991398.1
Type: Antitoxin
Protein ID: WP_035991398.1
Location: 2769814..2770911 (1098 bp)
Type: Others
Protein ID: WP_035990998.1
Type: Others
Protein ID: WP_035990998.1
Location: 2771119..2771583 (465 bp)
Type: Others
Protein ID: WP_035990996.1
Type: Others
Protein ID: WP_035990996.1
Location: 2771720..2772604 (885 bp)
Type: Others
Protein ID: WP_035990994.1
Type: Others
Protein ID: WP_035990994.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K788_RS12285 | 2764260..2765216 | - | 957 | WP_035991011.1 | sugar ABC transporter substrate-binding protein | - |
| K788_RS12290 | 2765772..2766410 | + | 639 | WP_035991009.1 | LysE family translocator | - |
| K788_RS12295 | 2766453..2767430 | - | 978 | WP_035991007.1 | magnesium/cobalt transporter CorA | - |
| K788_RS12300 | 2767635..2768108 | - | 474 | WP_082624872.1 | hypothetical protein | - |
| K788_RS12305 | 2768209..2768637 | - | 429 | WP_082624873.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| K788_RS12310 | 2768624..2768869 | - | 246 | WP_035991398.1 | DNA-binding protein | Antitoxin |
| K788_RS12315 | 2769038..2769658 | + | 621 | WP_035991001.1 | ATP-binding protein | - |
| K788_RS12320 | 2769814..2770911 | - | 1098 | WP_035990998.1 | saccharopine dehydrogenase NADP-binding domain-containing protein | - |
| K788_RS12325 | 2771119..2771583 | - | 465 | WP_035990996.1 | Lrp/AsnC family transcriptional regulator | - |
| K788_RS12330 | 2771720..2772604 | - | 885 | WP_035990994.1 | LysR family transcriptional regulator | - |
| K788_RS12335 | 2772758..2773270 | + | 513 | WP_035990992.1 | Spy/CpxP family protein refolding chaperone | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 143 a.a. Molecular weight: 15657.83 Da Isoelectric Point: 7.4682
>T57169 WP_082624873.1 NZ_CP012746:c2768637-2768209 [Paraburkholderia caribensis MBA4]
VYLIDTNVISEMRKSSRANPGVQAFFETAKEGGHRLYLSVVTVGELRRGVDLIRHRGDKFQALRLEGWLDTIMNSFSSHI
LNVGTDVAQTWGHLRVPDAGHALDKLIAATALIYNLTVVTRNVADFDGTGARVLNPFQLPDA
VYLIDTNVISEMRKSSRANPGVQAFFETAKEGGHRLYLSVVTVGELRRGVDLIRHRGDKFQALRLEGWLDTIMNSFSSHI
LNVGTDVAQTWGHLRVPDAGHALDKLIAATALIYNLTVVTRNVADFDGTGARVLNPFQLPDA
Download Length: 429 bp
>T57169 NZ_CP012746:c2768637-2768209 [Paraburkholderia caribensis MBA4]
GTGTATTTGATTGATACCAATGTAATCAGCGAAATGCGCAAGAGCAGCCGCGCCAATCCGGGCGTACAGGCTTTTTTCGA
AACGGCGAAGGAAGGCGGGCATCGCCTGTATCTGTCCGTCGTGACGGTCGGCGAGCTGCGGCGCGGCGTCGACCTGATCC
GGCATCGGGGCGACAAGTTCCAGGCGTTGCGCCTGGAAGGCTGGCTCGACACGATCATGAATTCGTTCAGCAGCCACATC
CTGAATGTCGGCACCGACGTCGCGCAGACGTGGGGCCATCTGCGCGTGCCCGACGCCGGGCACGCGCTGGACAAACTGAT
CGCGGCCACGGCCCTGATCTACAACCTGACTGTCGTGACGCGCAACGTGGCAGACTTCGATGGCACGGGCGCACGGGTGC
TCAATCCGTTCCAGCTTCCTGACGCATGA
GTGTATTTGATTGATACCAATGTAATCAGCGAAATGCGCAAGAGCAGCCGCGCCAATCCGGGCGTACAGGCTTTTTTCGA
AACGGCGAAGGAAGGCGGGCATCGCCTGTATCTGTCCGTCGTGACGGTCGGCGAGCTGCGGCGCGGCGTCGACCTGATCC
GGCATCGGGGCGACAAGTTCCAGGCGTTGCGCCTGGAAGGCTGGCTCGACACGATCATGAATTCGTTCAGCAGCCACATC
CTGAATGTCGGCACCGACGTCGCGCAGACGTGGGGCCATCTGCGCGTGCCCGACGCCGGGCACGCGCTGGACAAACTGAT
CGCGGCCACGGCCCTGATCTACAACCTGACTGTCGTGACGCGCAACGTGGCAGACTTCGATGGCACGGGCGCACGGGTGC
TCAATCCGTTCCAGCTTCCTGACGCATGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8938.90 Da Isoelectric Point: 4.2208
>AT57169 WP_035991398.1 NZ_CP012746:c2768869-2768624 [Paraburkholderia caribensis MBA4]
MANLLVRNLDDALVQNLREQAAAHGRSVEAEHREILAQALFQPRKLSFAELLMSMPDVGDDADFERRNDATDDSGGPGVF
D
MANLLVRNLDDALVQNLREQAAAHGRSVEAEHREILAQALFQPRKLSFAELLMSMPDVGDDADFERRNDATDDSGGPGVF
D
Download Length: 246 bp
>AT57169 NZ_CP012746:c2768869-2768624 [Paraburkholderia caribensis MBA4]
ATGGCAAATCTTTTGGTCCGAAATCTGGACGATGCGTTGGTGCAGAACCTGCGTGAGCAGGCCGCGGCTCACGGGCGCAG
CGTCGAAGCAGAGCATCGGGAAATTCTGGCGCAGGCGCTTTTTCAGCCCAGGAAGCTCAGCTTCGCGGAGTTGCTGATGA
GCATGCCCGACGTCGGCGACGACGCCGACTTCGAGCGCCGCAATGACGCAACTGACGATAGCGGGGGACCGGGTGTATTT
GATTGA
ATGGCAAATCTTTTGGTCCGAAATCTGGACGATGCGTTGGTGCAGAACCTGCGTGAGCAGGCCGCGGCTCACGGGCGCAG
CGTCGAAGCAGAGCATCGGGAAATTCTGGCGCAGGCGCTTTTTCAGCCCAGGAAGCTCAGCTTCGCGGAGTTGCTGATGA
GCATGCCCGACGTCGGCGACGACGCCGACTTCGAGCGCCGCAATGACGCAACTGACGATAGCGGGGGACCGGGTGTATTT
GATTGA