Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2173996..2174141 Replicon chromosome
Accession NZ_CP012745
Organism Klebsiella pneumoniae subsp. pneumoniae strain TGH13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2174032..2174134 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2173996..2174141 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOG30_RS10670 2169126..2171186 + 2061 WP_004151449.1 oligopeptidase B -
AOG30_RS10675 2171190..2171849 - 660 WP_002911407.1 exodeoxyribonuclease X -
AOG30_RS10680 2171928..2172158 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AOG30_RS10685 2172271..2172645 + 375 WP_060577972.1 CopC domain-containing protein YobA -
AOG30_RS10690 2172649..2173518 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AOG30_RS10695 2173535..2173873 + 339 WP_002911404.1 YebY family protein -
- 2173996..2174141 - 146 - - Antitoxin
- 2174032..2174134 + 103 - - Toxin
AOG30_RS28110 2174510..2174653 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
AOG30_RS10705 2174758..2175726 - 969 WP_014907334.1 VirK/YbjX family protein -
AOG30_RS10710 2175883..2176536 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
AOG30_RS10715 2176533..2176724 - 192 WP_002911395.1 YebW family protein -
AOG30_RS10720 2176822..2177061 - 240 WP_002911393.1 YebV family protein -
AOG30_RS10725 2177177..2178610 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T57155 NZ_CP012745:2174032-2174134 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT57155 NZ_CP012745:c2174141-2173996 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References