Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1934876..1935021 Replicon chromosome
Accession NZ_CP012744
Organism Klebsiella pneumoniae subsp. pneumoniae strain TGH10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1934912..1935014 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1934876..1935021 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOG31_RS09730 1930006..1932066 + 2061 WP_004151449.1 oligopeptidase B -
AOG31_RS09735 1932070..1932729 - 660 WP_032425085.1 exodeoxyribonuclease X -
AOG31_RS09740 1932808..1933038 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AOG31_RS09745 1933151..1933525 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AOG31_RS09750 1933529..1934398 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AOG31_RS09755 1934415..1934753 + 339 WP_016529031.1 YebY family protein -
- 1934876..1935021 - 146 - - Antitoxin
- 1934912..1935014 + 103 - - Toxin
AOG31_RS29135 1935389..1935532 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AOG31_RS09765 1935637..1936605 - 969 WP_004151446.1 VirK/YbjX family protein -
AOG31_RS09770 1936762..1937415 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AOG31_RS09775 1937412..1937603 - 192 WP_002911395.1 YebW family protein -
AOG31_RS09780 1937701..1937940 - 240 WP_002911393.1 YebV family protein -
AOG31_RS09785 1938056..1939489 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T57136 NZ_CP012744:1934912-1935014 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT57136 NZ_CP012744:c1935021-1934876 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References