Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2030441..2030586 Replicon chromosome
Accession NZ_CP012743
Organism Klebsiella pneumoniae subsp. pneumoniae strain TGH8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2030477..2030579 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2030441..2030586 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOD72_RS10070 2025571..2027631 + 2061 WP_004151449.1 oligopeptidase B -
AOD72_RS10075 2027635..2028294 - 660 WP_032425085.1 exodeoxyribonuclease X -
AOD72_RS10080 2028373..2028603 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AOD72_RS10085 2028716..2029090 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AOD72_RS10090 2029094..2029963 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AOD72_RS10095 2029980..2030318 + 339 WP_016529031.1 YebY family protein -
- 2030441..2030586 - 146 - - Antitoxin
- 2030477..2030579 + 103 - - Toxin
AOD72_RS29450 2030954..2031097 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AOD72_RS10105 2031202..2032170 - 969 WP_004151446.1 VirK/YbjX family protein -
AOD72_RS10110 2032327..2032980 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AOD72_RS10115 2032977..2033168 - 192 WP_002911395.1 YebW family protein -
AOD72_RS10120 2033266..2033505 - 240 WP_002911393.1 YebV family protein -
AOD72_RS10125 2033621..2035054 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T57120 NZ_CP012743:2030477-2030579 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT57120 NZ_CP012743:c2030586-2030441 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References