57116

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 833404..834751 Replicon chromosome
Accession NZ_CP012740
Organism Vibrio vulnificus strain FORC_017

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag FORC17_RS18580 Protein ID WP_065091110.1
Coordinates 833810..834751 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A854GL31
Locus tag FORC17_RS18575 Protein ID WP_017422919.1
Coordinates 833404..833808 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC17_RS18555 828595..829053 + 459 WP_015727851.1 hypothetical protein -
FORC17_RS18560 829243..829989 + 747 WP_065091364.1 carbon-nitrogen hydrolase family protein -
FORC17_RS18565 830490..831254 + 765 WP_065091108.1 nucleotidyltransferase domain-containing protein -
FORC17_RS18570 831310..833070 - 1761 WP_065091109.1 ABC transporter ATP-binding protein/permease -
FORC17_RS18575 833404..833808 + 405 WP_017422919.1 hypothetical protein Antitoxin
FORC17_RS18580 833810..834751 + 942 WP_065091110.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FORC17_RS18585 835420..837585 + 2166 WP_065091111.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 36143.55 Da        Isoelectric Point: 5.1741

>T57116 WP_065091110.1 NZ_CP012740:833810-834751 [Vibrio vulnificus]
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKGVRKAWVNEIEQAIIHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SVVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFTSFKRIAESLIEKI

Download         Length: 942 bp

>T57116 NZ_CP012740:833810-834751 [Vibrio vulnificus]
ATGAACGCACTAAAACAACAATTTCTTGAGGTTTCCGACGCGCTTGAGCTCGGAAACCCTGCCATCATTGAAAAAGATTT
CTGGGTCGTTGCCTTACTTGCCGAGCTAGCAAAAGTTTCTCCTGAATATCATCAAATGGTCTTTTCCGGCGGCACGGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCAAGCGTTTGATGAA
CTGAGTCGAGCAAAAAAGAAAGGCGTTAGAAAGGCATGGGTTAACGAGATTGAACAGGCGATCATTCATTCAGAACGATT
TACCGTTGAAACGCGATCTGTGCGAGATGAGTACCGTTACGTTGAGTTTGAACTCAGATATCCGCAACAGTTTAGTCAAG
TTCCCTGTCTTCGTCCCATCATTAAGTTAGAGTTAATCGAAACCATTCCATTACTGGATGTGGAGTCGCGCAGCATTCAA
TCAGTGGTTGCAGAGTTGTACCAACAACCGCACGAAGTGAGTTCATTTGATTGCGTCTCTGTCTATGCCACATTGGTTGA
AAAAATCATTTCGATGCTGCGCCGTACAATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTTTGGTTCGCC
ATATCTACGATGTGCATTGCATAACAAAGCTTACAATGTCTGAACTCAACTCGATTGACGGCCTTTTCAAAGCGGTATTG
GAAGAAGATATTGCCCGCTTTGGCAATCAACATGCAGAGTTTGTTGCCAACCCCAAACAAGAGCTACAACTTGGCCTCAA
AGAGCTTGAGGAAAATCCCATTTTCCGCCAACGTTTTCAGGACTTTGTCACACCAATGGTGTTTAACACTGAGCCCCATG
ATTTTGATACCTGCTTTACCTCATTCAAGCGCATTGCCGAGTCGCTAATTGAAAAAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15115.43 Da        Isoelectric Point: 10.6258

>AT57116 WP_017422919.1 NZ_CP012740:833404-833808 [Vibrio vulnificus]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT57116 NZ_CP012740:833404-833808 [Vibrio vulnificus]
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGACGGATT
TGCAAGTTACGACCAAATAGGTCGGGCATTGAGGCAGCTTGTACAGCAAGGGGAGCTAATGAAGCTTGGCTATGGTTTGT
ATACCAAAGCAAGAATCAATAGCCTCACAGGTAAGCCTATGCCTACCAATCCAGGTGGCACCGATGCTCTTGTACGTGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAAATGGATAGTCTATCGCAACAAAGTCTTTCAGGTGCGAGTACCCAAATTCC
ATCCTCTGTTCACTATTCATGGAACCCAAAACAGTTTAATCGCAAACTGGTGGTTGGTAGCCGTGTGCTGAACTTGCCAA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854GL31

References