Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4208916..4209150 | Replicon | chromosome |
| Accession | NZ_CP012735 | ||
| Organism | Shigella flexneri 1a strain 0228 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4208917..4209020 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4208916..4209150 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AOT98_RS23025 | 4204362..4204829 | - | 468 | Protein_4128 | DNA-binding transcriptional regulator PgrR | - |
| AOT98_RS23030 | 4204893..4205203 | + | 311 | Protein_4129 | transposase | - |
| AOT98_RS28420 | 4205246..4206441 | - | 1196 | Protein_4130 | IS3 family transposase | - |
| AOT98_RS23050 | 4206496..4207344 | + | 849 | Protein_4131 | IS3-like element IS600 family transposase | - |
| AOT98_RS28425 | 4207461..4207742 | + | 282 | WP_005127484.1 | excisionase | - |
| AOT98_RS30485 | 4207708..4208785 | + | 1078 | Protein_4133 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4208916..4209150 | + | 235 | - | - | Antitoxin |
| - | 4208917..4209020 | - | 104 | - | - | Toxin |
| AOT98_RS23065 | 4209178..4209519 | - | 342 | WP_000976476.1 | YebY family protein | - |
| AOT98_RS28440 | 4209532..4210404 | - | 873 | Protein_4135 | copper homeostasis membrane protein CopD | - |
| AOT98_RS23080 | 4210408..4210782 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| AOT98_RS23085 | 4210921..4211151 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| AOT98_RS23090 | 4211253..4211909 | + | 657 | Protein_4138 | carbon-nitrogen hydrolase family protein YobB | - |
| AOT98_RS23095 | 4211933..4212595 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T57097 NZ_CP012735:c4209020-4208917 [Shigella flexneri 1a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT57097 NZ_CP012735:4208916-4209150 [Shigella flexneri 1a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
