Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-PumB/COG3657-dnstrm_HI1420 |
Location | 65131..65741 | Replicon | plasmid unnamed |
Accession | NZ_CP012688 | ||
Organism | Ralstonia solanacearum strain UY031 |
Toxin (Protein)
Gene name | relE | Uniprot ID | B5SAJ5 |
Locus tag | RSUY_RS15980 | Protein ID | WP_003262835.1 |
Coordinates | 65433..65741 (-) | Length | 103 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | RSUY_RS15975 | Protein ID | WP_003262836.1 |
Coordinates | 65131..65436 (-) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RSUY_RS15955 | 61238..61648 | + | 411 | WP_003262840.1 | acyl-CoA thioesterase | - |
RSUY_RS15960 | 61678..62070 | + | 393 | WP_003262838.1 | RidA family protein | - |
RSUY_RS15965 | 62418..63008 | + | 591 | WP_020957579.1 | hypothetical protein | - |
RSUY_RS15970 | 63607..64920 | - | 1314 | WP_003262837.1 | metabolite/H+ symporter | - |
RSUY_RS15975 | 65131..65436 | - | 306 | WP_003262836.1 | putative addiction module antidote protein | Antitoxin |
RSUY_RS15980 | 65433..65741 | - | 309 | WP_003262835.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
RSUY_RS15985 | 65817..67016 | - | 1200 | WP_003262834.1 | MFS transporter | - |
RSUY_RS15990 | 67144..67962 | - | 819 | WP_039556864.1 | GntR family transcriptional regulator | - |
RSUY_RS15995 | 68132..68683 | - | 552 | WP_039556867.1 | helix-turn-helix transcriptional regulator | - |
RSUY_RS16000 | 68816..69415 | + | 600 | WP_039556871.1 | GNAT family N-acetyltransferase | - |
RSUY_RS16005 | 69681..70115 | + | 435 | WP_003274507.1 | VOC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | cheY / cyaB / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA | 1..1999545 | 1999545 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11900.72 Da Isoelectric Point: 7.2450
>T56978 WP_003262835.1 NZ_CP012688:c65741-65433 [Ralstonia solanacearum]
MLTIRTTELFDDWFCSLRDKAAQRRIQVRIDRLQMGHLGDMKAVRDGIRELRIDHGPGYRLYFVQHGVVLIVLLCGGDKS
TQETDIRRAIDLSRRLDVDDME
MLTIRTTELFDDWFCSLRDKAAQRRIQVRIDRLQMGHLGDMKAVRDGIRELRIDHGPGYRLYFVQHGVVLIVLLCGGDKS
TQETDIRRAIDLSRRLDVDDME
Download Length: 309 bp
>T56978 NZ_CP012688:c65741-65433 [Ralstonia solanacearum]
ATGCTGACGATCCGCACGACCGAACTCTTTGACGACTGGTTTTGCAGCCTCCGCGACAAGGCTGCGCAACGCCGCATCCA
GGTGCGCATCGACCGCCTGCAGATGGGTCACCTGGGCGACATGAAAGCGGTACGTGACGGCATCCGCGAGCTGCGGATCG
ATCATGGGCCGGGCTACCGCTTGTACTTCGTGCAGCACGGCGTCGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCG
ACACAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA
ATGCTGACGATCCGCACGACCGAACTCTTTGACGACTGGTTTTGCAGCCTCCGCGACAAGGCTGCGCAACGCCGCATCCA
GGTGCGCATCGACCGCCTGCAGATGGGTCACCTGGGCGACATGAAAGCGGTACGTGACGGCATCCGCGAGCTGCGGATCG
ATCATGGGCCGGGCTACCGCTTGTACTTCGTGCAGCACGGCGTCGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCG
ACACAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11038.72 Da Isoelectric Point: 8.0667
>AT56978 WP_003262836.1 NZ_CP012688:c65436-65131 [Ralstonia solanacearum]
MTMAQRTLKTRPWDSAEHLRTEADMAAYLNACLEEAGDDPAFITHALGVVARARGMTRLARETGITREGLYKALSEDGNP
SFATMLKVIRALGIRLHAVPA
MTMAQRTLKTRPWDSAEHLRTEADMAAYLNACLEEAGDDPAFITHALGVVARARGMTRLARETGITREGLYKALSEDGNP
SFATMLKVIRALGIRLHAVPA
Download Length: 306 bp
>AT56978 NZ_CP012688:c65436-65131 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCCTCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAGGCGGACATGGCCGC
CTATCTCAACGCCTGCCTGGAAGAAGCCGGGGACGACCCGGCGTTCATTACGCACGCGCTGGGCGTGGTCGCGCGTGCGC
GCGGCATGACCCGGCTCGCCCGCGAGACCGGGATCACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAACCCG
AGCTTTGCGACCATGCTGAAGGTCATCCGGGCACTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA
ATGACGATGGCCCAACGCACCCTCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAGGCGGACATGGCCGC
CTATCTCAACGCCTGCCTGGAAGAAGCCGGGGACGACCCGGCGTTCATTACGCACGCGCTGGGCGTGGTCGCGCGTGCGC
GCGGCATGACCCGGCTCGCCCGCGAGACCGGGATCACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAACCCG
AGCTTTGCGACCATGCTGAAGGTCATCCGGGCACTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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