Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 469861..470494 Replicon chromosome
Accession NZ_CP012687
Organism Ralstonia solanacearum strain UY031

Toxin (Protein)


Gene name vapC Uniprot ID A0A850FL68
Locus tag RSUY_RS01960 Protein ID WP_003263272.1
Coordinates 470081..470494 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F6FXL0
Locus tag RSUY_RS01955 Protein ID WP_003263271.1
Coordinates 469861..470094 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RSUY_RS01940 465435..466724 - 1290 WP_003263268.1 MFS transporter -
RSUY_RS01945 466732..468000 - 1269 WP_094472172.1 AGE family epimerase/isomerase -
RSUY_RS01950 468196..469803 + 1608 WP_039557249.1 glucan biosynthesis protein -
RSUY_RS01955 469861..470094 + 234 WP_003263271.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RSUY_RS01960 470081..470494 + 414 WP_003263272.1 PIN domain-containing protein Toxin
RSUY_RS01965 470469..471095 - 627 WP_003263273.1 DUF1415 domain-containing protein -
RSUY_RS01970 471306..471677 + 372 WP_003263275.1 hypothetical protein -
RSUY_RS01975 471753..473249 - 1497 WP_003263276.1 glycerol kinase GlpK -
RSUY_RS01980 473421..475157 - 1737 WP_003266149.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-116)

Antitoxin

SpoVT-AbrB domain

(5-40)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 14843.14 Da        Isoelectric Point: 5.9701

>T56977 WP_003263272.1 NZ_CP012687:470081-470494 [Ralstonia solanacearum]
MPAAEAFFDSNIVLYLLSADAAKADAAEALLMAGGAVSVQVLNETTHVMRRKLAMPWHAIEAVQEAVRAQCRVEPLTVET
HDLGRHLAQRYGLSVYDALIVAAASLAGCRVLYSEDMQHGLVIEQRLRVVNPFVASA

Download         Length: 414 bp

>T56977 NZ_CP012687:470081-470494 [Ralstonia solanacearum]
ATGCCCGCGGCTGAGGCGTTTTTCGACAGCAACATCGTGCTGTACCTGCTGTCGGCCGATGCCGCCAAGGCCGATGCGGC
GGAAGCGCTACTGATGGCCGGCGGTGCCGTCAGCGTGCAGGTGCTCAACGAAACGACGCACGTGATGCGCCGCAAGCTCG
CCATGCCGTGGCACGCGATCGAAGCGGTGCAGGAAGCTGTGCGCGCGCAATGCCGGGTCGAGCCGCTGACGGTCGAAACC
CATGATCTCGGGCGGCATCTTGCGCAGCGCTATGGATTGTCGGTCTATGACGCGCTGATCGTCGCCGCGGCGTCGCTGGC
CGGTTGCCGCGTTCTGTATTCCGAGGACATGCAGCACGGCCTGGTGATCGAGCAGCGTCTGCGCGTCGTCAATCCTTTTG
TCGCGTCGGCGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8664.82 Da        Isoelectric Point: 8.7288

>AT56977 WP_003263271.1 NZ_CP012687:469861-470094 [Ralstonia solanacearum]
MQVSKWGNSLAIRLPAAVVEALGLHEGDDVEVVVAGERSFGVRRKRSARELFERLHQYRGKLPADFIFERDDANARG

Download         Length: 234 bp

>AT56977 NZ_CP012687:469861-470094 [Ralstonia solanacearum]
ATGCAAGTCTCGAAATGGGGCAACAGCCTCGCCATCCGGCTGCCCGCAGCCGTCGTGGAGGCGCTTGGACTGCACGAAGG
CGACGACGTCGAGGTGGTGGTGGCGGGCGAACGCTCGTTTGGTGTGCGCCGCAAGCGTTCCGCGCGTGAGTTGTTTGAGC
GGCTCCACCAATACCGCGGCAAGCTGCCCGCCGACTTCATCTTCGAGCGCGACGACGCCAATGCCCGCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A850FL68

Antitoxin

Source ID Structure
AlphaFold DB F6FXL0

References