Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 2487..3034 Replicon plasmid p33673_IncF
Accession NZ_CP012683
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain 33676

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag SE15cs_RS26485 Protein ID WP_071845783.1
Coordinates 2753..3034 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag SE15cs_RS24185 Protein ID WP_054088336.1
Coordinates 2487..2756 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SE15cs_RS24175 159..416 + 258 WP_001541895.1 replication regulatory protein RepA -
SE15cs_RS26470 648..722 + 75 WP_061357229.1 RepA leader peptide Tap -
SE15cs_RS24180 715..1572 + 858 WP_039002220.1 incFII family plasmid replication initiator RepA -
SE15cs_RS24185 2487..2756 + 270 WP_054088336.1 hypothetical protein Antitoxin
SE15cs_RS26485 2753..3034 + 282 WP_071845783.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SE15cs_RS24190 3047..3895 - 849 Protein_5 IS91 family transposase -
SE15cs_RS24205 5280..5645 - 366 WP_054088337.1 hypothetical protein -
SE15cs_RS27570 5890..6126 + 237 WP_074152073.1 colicin V immunity protein -
SE15cs_RS24210 6104..6414 + 311 Protein_9 colicin V -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..112639 112639


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(76-174)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T56954 WP_071845783.1 NZ_CP012683:2753-3034 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T56954 NZ_CP012683:2753-3034 [Salmonella enterica subsp. enterica serovar Typhimurium]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 11553.68 Da        Isoelectric Point: 12.7493

>AT56954 WP_054088336.1 NZ_CP012683:2487-2756 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKK

Download         Length: 270 bp

>AT56954 NZ_CP012683:2487-2756 [Salmonella enterica subsp. enterica serovar Typhimurium]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References