Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 2978718..2979229 Replicon chromosome
Accession NZ_CP012661
Organism Defluviimonas alba strain cai42

Toxin (Protein)


Gene name relB Uniprot ID A0A159Z6U1
Locus tag AKL17_RS14175 Protein ID WP_066814406.1
Coordinates 2978718..2978978 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag AKL17_RS14180 Protein ID WP_066814408.1
Coordinates 2978975..2979229 (-) Length 85 a.a.

Genomic Context

AKL17_RS14155AKL17_RS14160AKL17_RS14165AKL17_RS14170AKL17_RS14175AKL17_RS14180AKL17_RS14185AKL17_RS14190AKL17_RS14195
Location: 2973849..2974985 (1137 bp)
Type: Others
Protein ID: WP_084739728.1
Location: 2974994..2977042 (2049 bp)
Type: Others
Protein ID: WP_066814402.1
Location: 2977039..2978106 (1068 bp)
Type: Others
Protein ID: WP_066818557.1
Location: 2978130..2978597 (468 bp)
Type: Others
Protein ID: WP_066814404.1
Location: 2978718..2978978 (261 bp)
Type: Toxin
Protein ID: WP_066814406.1
Location: 2978975..2979229 (255 bp)
Type: Antitoxin
Protein ID: WP_066814408.1
Location: 2979276..2979665 (390 bp)
Type: Others
Protein ID: WP_066814410.1
Location: 2979662..2981647 (1986 bp)
Type: Others
Protein ID: WP_066814412.1
Location: 2981798..2983764 (1967 bp)
Type: Others
Protein ID: Protein_2902
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AKL17_RS141552973849..2974985+1137WP_084739728.1polysaccharide biosynthesis/export family protein-
AKL17_RS141602974994..2977042+2049WP_066814402.1capsular polysaccharide biosynthesis protein-
AKL17_RS141652977039..2978106-1068WP_066818557.1bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD-
AKL17_RS141702978130..2978597-468WP_066814404.1transcriptional regulator NrdR-
AKL17_RS141752978718..2978978-261WP_066814406.1Txe/YoeB family addiction module toxinToxin
AKL17_RS141802978975..2979229-255WP_066814408.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
AKL17_RS141852979276..2979665-390WP_066814410.1hypothetical protein-
AKL17_RS141902979662..2981647-1986WP_066814412.1RNA polymerase sigma factor RpoD-
AKL17_RS141952981798..2983764-1967Protein_2902DNA primase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10174.66 Da        Isoelectric Point: 9.0291

>T56907 WP_066814406.1 NZ_CP012661:c2978978-2978718 [Defluviimonas alba]
MTLTFWDKAWDDYLYWQATDKATLRKINALIKECLRHPFEGTGKPEPLKGDLAGFWSRRIDREHRLVYRATAGTLEILQC
RYHYGA

Download         Length: 261 bp

>T56907 NZ_CP012661:c2978978-2978718 [Defluviimonas alba]
ATGACCCTGACCTTCTGGGACAAAGCCTGGGACGATTACCTCTACTGGCAGGCCACCGACAAGGCGACGCTCCGCAAGAT
CAACGCGCTGATAAAGGAATGCCTGCGCCACCCGTTCGAAGGCACCGGCAAGCCCGAACCGCTGAAGGGCGATCTGGCGG
GTTTCTGGTCGCGCCGGATCGACCGCGAGCACCGCCTCGTCTATCGCGCCACGGCCGGGACGCTCGAAATCCTGCAATGC
CGCTACCACTACGGCGCTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9340.55 Da        Isoelectric Point: 4.7962

>AT56907 WP_066814408.1 NZ_CP012661:c2979229-2978975 [Defluviimonas alba]
MKTLSSTELRQTLSTVMDRVNDDHEPVIVTRATGKPVVMVSLEDWASMDETAYLLTSPENARRLRDGVAALNRGEGRPRD
LIGE

Download         Length: 255 bp

>AT56907 NZ_CP012661:c2979229-2978975 [Defluviimonas alba]
ATGAAAACCCTCTCCTCCACCGAACTCCGCCAGACCCTGTCCACCGTCATGGACCGCGTGAACGACGACCATGAGCCGGT
CATCGTGACCCGCGCCACCGGCAAGCCTGTCGTTATGGTCAGCCTCGAGGACTGGGCGAGCATGGATGAGACGGCCTATC
TCCTGACCAGCCCGGAAAACGCCCGGCGCTTGCGCGACGGGGTGGCGGCCCTGAACCGGGGCGAGGGGCGCCCGCGTGAC
CTGATCGGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A159Z6U1

Antitoxin

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Source
ID
Structure
No matching records found

References