Detailed information of TA system TA056907

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-YefM
• Location: 2978718..2979229
• Replicon: chromosome
• Accession: NZ_CP012661
• Organism: Defluviimonas alba strain cai42

Toxin (Protein)

• Gene name: relB
• Uniprot ID: A0A159Z6U1
• Locus tag: AKL17_RS14175
• Protein ID: WP_066814406.1
• Coordinates: 2978718..2978978 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: AKL17_RS14180
• Protein ID: WP_066814408.1
• Coordinates: 2978975..2979229 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AKL17_RS14155	2973849..2974985	+	1137	WP_084739728.1	polysaccharide biosynthesis/export family protein	-
AKL17_RS14160	2974994..2977042	+	2049	WP_066814402.1	capsular polysaccharide biosynthesis protein	-
AKL17_RS14165	2977039..2978106	-	1068	WP_066818557.1	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	-
AKL17_RS14170	2978130..2978597	-	468	WP_066814404.1	transcriptional regulator NrdR	-
AKL17_RS14175	2978718..2978978	-	261	WP_066814406.1	Txe/YoeB family addiction module toxin	Toxin
AKL17_RS14180	2978975..2979229	-	255	WP_066814408.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
AKL17_RS14185	2979276..2979665	-	390	WP_066814410.1	hypothetical protein	-
AKL17_RS14190	2979662..2981647	-	1986	WP_066814412.1	RNA polymerase sigma factor RpoD	-
AKL17_RS14195	2981798..2983764	-	1967	Protein_2902	DNA primase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10174.66 Da
• Isoelectric Point: 9.0291

>T56907 WP_066814406.1 NZ_CP012661:c2978978-2978718 [Defluviimonas alba]
MTLTFWDKAWDDYLYWQATDKATLRKINALIKECLRHPFEGTGKPEPLKGDLAGFWSRRIDREHRLVYRATAGTLEILQC
RYHYGA

Nucleotide

• Length: 261 bp

>T56907 NZ_CP012661:c2978978-2978718 [Defluviimonas alba]
ATGACCCTGACCTTCTGGGACAAAGCCTGGGACGATTACCTCTACTGGCAGGCCACCGACAAGGCGACGCTCCGCAAGAT
CAACGCGCTGATAAAGGAATGCCTGCGCCACCCGTTCGAAGGCACCGGCAAGCCCGAACCGCTGAAGGGCGATCTGGCGG
GTTTCTGGTCGCGCCGGATCGACCGCGAGCACCGCCTCGTCTATCGCGCCACGGCCGGGACGCTCGAAATCCTGCAATGC
CGCTACCACTACGGCGCTTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9340.55 Da
• Isoelectric Point: 4.7962

>AT56907 WP_066814408.1 NZ_CP012661:c2979229-2978975 [Defluviimonas alba]
MKTLSSTELRQTLSTVMDRVNDDHEPVIVTRATGKPVVMVSLEDWASMDETAYLLTSPENARRLRDGVAALNRGEGRPRD
LIGE

Nucleotide

• Length: 255 bp

>AT56907 NZ_CP012661:c2979229-2978975 [Defluviimonas alba]
ATGAAAACCCTCTCCTCCACCGAACTCCGCCAGACCCTGTCCACCGTCATGGACCGCGTGAACGACGACCATGAGCCGGT
CATCGTGACCCGCGCCACCGGCAAGCCTGTCGTTATGGTCAGCCTCGAGGACTGGGCGAGCATGGATGAGACGGCCTATC
TCCTGACCAGCCCGGAAAACGCCCGGCGCTTGCGCGACGGGGTGGCGGCCCTGAACCGGGGCGAGGGGCGCCCGCGTGAC
CTGATCGGCGAATGA

Structures

Toxin

• AlphaFold DB: A0A159Z6U1