Detailed information of TA system TA056902

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 1726533..1727314
• Replicon: chromosome
• Accession: NZ_CP012640
• Organism: Massilia sp. WG5

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: A0A0J1DDT1
• Locus tag: AM586_RS07655
• Protein ID: WP_047824126.1
• Coordinates: 1726533..1727012 (-)
• Length: 160 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: AM586_RS28560
• Protein ID: WP_197416415.1
• Coordinates: 1727009..1727314 (-)
• Length: 102 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AM586_RS07630	1722632..1723795	+	1164	WP_082439705.1	DUF418 domain-containing protein	-
AM586_RS07640	1723939..1725075	-	1137	WP_047824129.1	acyl-coA dehydrogenase-like protein	-
AM586_RS07650	1725307..1726518	+	1212	WP_047824128.1	formate-dependent phosphoribosylglycinamide formyltransferase	-
AM586_RS07655	1726533..1727012	-	480	WP_047824126.1	RES family NAD+ phosphorylase	Toxin
AM586_RS28560	1727009..1727314	-	306	WP_197416415.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
AM586_RS07675	1727926..1729137	-	1212	WP_047824122.1	aspartate/tyrosine/aromatic aminotransferase	-
AM586_RS07680	1729286..1731328	+	2043	WP_197416414.1	excinuclease ABC subunit UvrB	-
AM586_RS07685	1731466..1731957	+	492	WP_047824117.1	RICIN domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-146)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (54-98)

Sequences

Toxin

Protein

• Length: 160 a.a.
• Molecular weight: 17200.83 Da
• Isoelectric Point: 10.0601

>T56902 WP_047824126.1 NZ_CP012640:c1727012-1726533 [Massilia sp. WG5]
VSVVWRIATDTPGYTADDLTGAGAKQSGGRWNRPGNAMLYCASNISLAVLETFVRLKAGGLPLNRYLVALTIPDAVWKSA
TWMPAPPVGWDAIPAGKVSLDEGDRWLKANRSAVLIVPSVIVGEESNVLINPLHPDAGRIEARKVRKWGYDPRLMRPGS

Nucleotide

• Length: 480 bp

>T56902 NZ_CP012640:c1727012-1726533 [Massilia sp. WG5]
GTGAGCGTCGTCTGGCGCATCGCGACCGATACGCCCGGCTATACCGCAGATGACCTGACAGGCGCGGGCGCCAAGCAGTC
CGGCGGCCGCTGGAACCGGCCCGGCAACGCCATGCTCTACTGCGCCAGCAATATCTCGCTGGCGGTCCTCGAAACCTTCG
TGCGCCTGAAAGCGGGCGGCCTGCCGCTGAACCGCTACCTGGTGGCGCTGACGATTCCCGATGCGGTGTGGAAGAGCGCG
ACCTGGATGCCCGCGCCGCCGGTGGGCTGGGATGCGATCCCGGCCGGCAAGGTGAGCCTGGACGAGGGCGACCGATGGCT
GAAGGCGAATCGCAGCGCGGTGCTGATCGTGCCATCGGTGATCGTGGGCGAAGAGAGCAATGTGCTGATCAATCCGCTGC
ATCCGGATGCCGGGCGCATCGAGGCCAGGAAGGTCCGGAAGTGGGGCTACGATCCCAGGCTGATGCGCCCGGGATCCTGA

Antitoxin

Protein

• Length: 102 a.a.
• Molecular weight: 11146.69 Da
• Isoelectric Point: 4.2397

>AT56902 WP_197416415.1 NZ_CP012640:c1727314-1727009 [Massilia sp. WG5]
MLDIATATVNRKASRNEALSREDSEKVVGMAKLIGQVETMLEESGDPDLMKDFDAARWLTHWMEEPIPALGGATPAEYMD
TIEGQEMISKLLARMQTGAYA

Nucleotide

• Length: 306 bp

>AT56902 NZ_CP012640:c1727314-1727009 [Massilia sp. WG5]
ATGCTCGACATCGCCACGGCCACCGTCAACCGCAAGGCCAGCCGCAACGAAGCCCTGTCGCGCGAAGACAGCGAAAAAGT
GGTCGGCATGGCAAAACTGATCGGGCAGGTCGAGACCATGCTCGAAGAATCCGGCGATCCGGACCTCATGAAGGATTTCG
ACGCCGCCCGCTGGCTCACCCACTGGATGGAAGAGCCGATCCCGGCGCTCGGCGGCGCCACGCCCGCCGAATACATGGAC
ACCATCGAAGGTCAGGAGATGATCTCCAAACTGCTCGCAAGGATGCAGACAGGGGCCTACGCGTGA

Structures

Toxin

• AlphaFold DB: A0A0J1DDT1