Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2278053..2278321 Replicon chromosome
Accession NZ_CP012625
Organism Escherichia coli strain SF-468

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2278181..2278283 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2278053..2278321 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AN206_RS11460 2274607..2275269 - 663 WP_000944256.1 exodeoxyribonuclease X -
AN206_RS11465 2275292..2275948 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
AN206_RS11470 2276050..2276280 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AN206_RS11475 2276419..2276793 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AN206_RS11480 2276797..2277669 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
AN206_RS11485 2277682..2278023 + 342 WP_000984819.1 YebY family protein -
- 2278053..2278321 - 269 - - Antitoxin
- 2278181..2278283 + 103 - - Toxin
AN206_RS11495 2278418..2279074 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
AN206_RS11500 2279075..2279266 - 192 WP_001296140.1 YebW family protein -
AN206_RS11505 2279371..2279607 - 237 WP_001295499.1 DUF1480 family protein -
AN206_RS11510 2279725..2281164 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T56794 NZ_CP012625:2278181-2278283 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT56794 NZ_CP012625:c2278321-2278053 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References